Traditional textile testing does not allow for the efficient separation and quantitative analysis of complex chemical components,and High-performance liquid chromatography is an accurate and efficient analytical tool,can achieve the effective separation of the various components of samples,facilitate the identification of potentially harmful substances,make textiles in line with relevant safety standards,provide important support for the development of the industry.In this paper,the basis of High-performance liquid chromatography technology is analyzed,and then the application of High-performance liquid chromatography technology in textile testing is analyzed to improve the accuracy and validity of testing results.