基于神经影像技术的针灸治疗功能性肠病研究系统评价
Acupuncture Therapy for Functional Bowel Disorders Based on Neuroimaging Technology:A Systematic Review
李思扬 1何雨杞 1张攀 2毛杨科 2曾芳 3尹涛3
作者信息
- 1. 成都中医药大学针灸推拿学院(成都 610075)
- 2. 成都中医药大学针灸推拿学院(成都 610075);成都中医药大学针灸脑科学研究中心(成都 611137)
- 3. 成都中医药大学针灸推拿学院(成都 610075);成都中医药大学针灸脑科学研究中心(成都 611137);针灸与时间生物学四川省重点实验室(成都 610075)
- 折叠
摘要
目的 系统评价针刺治疗功能性肠病(FBD)的神经影像学研究,探讨针刺治疗FBD的中枢机制.方法 系统检索中国知网、万方、Web of Science、Embase、PubMed 5个数据库,筛选纳入基于神经影像技术的针刺治疗FBD临床研究,分析总结研究设计,整理针刺干预对FBD患者脑功能活动模式的影响.结果 共筛选304篇,纳入9篇文献,这些研究从即时影响和长期效应两个方面探讨了针刺治疗FBD的中枢机制,发现单次针刺显著影响了 FBD患者扣带回、丘脑等区域功能活动,疗程针刺治疗显著调节了 FBD患者前扣带回、脑岛、海马等区域的功能活动及连接模式.结论 针刺可能通过调节FBD患者前扣带回、脑岛、丘脑等区域的功能活动及连接模式实现治疗作用.
Abstract
Objective To systematically review neuroimaging studies on the acupuncture treatment of functional bowel disorders(FBD)and explore the central mechanisms involved in the acupuncture treatment of FBD.Methods Five databases such as China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform,Web of Science,EMBASE,and PubMed were retrieved.Studies focused on acupuncture treatment of FBD based on neuroimaging techniques were included.Research designs were analyzed and summarized,and the impact of acupuncture intervention on brain activity patterns in FBD patients was compiled.Results Out of 304 literatures screened,9 literatures were identified.These studies explored the central mechanisms of acupuncture treatment for FBD from both immediate and long-term effects.It was found that a single session of acupuncture significantly influenced brain activity in regions such as the cingulate cortex and thalamus in FBD patients.Course-based acupuncture treatment significantly modulated functional activities and connectivity patterns in regions like the anterior cingulate cortex,insula,and hippocampus in FBD patients.Conclusion Acupuncture may exert its therapeutic effects by modulating functional activities and connectivity patterns in areas such as the anterior cingulate cortex,insula,and thalamus in FBD patients.
关键词
针刺/功能性肠病/肠易激综合征/神经影像/系统评价/中西医结合Key words
acupuncture/functional bowel disorders/irritable bowel syndrome/neuroimaging/systematic review/integrative medicine引用本文复制引用
基金项目
国家自然科学基金面上项目(81973960)
国家自然科学基金青年基金项目(82105032)
四川省科技厅青年科技创新研究团队项目(2019JDTD0011)
四川省科技厅科技创新苗子工程重点项目(2020JDRC0105)
成都中医药大学2022-2023年大学生科研实践创新项目(ky-2023079)
出版年
2024
国家科技期刊平台
NSTL
万方数据