首页|基于中医证素构建冠心病PCI术后风险预测模型

基于中医证素构建冠心病PCI术后风险预测模型

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主要不良心血管事件(MACEs)是冠状动脉粥样硬化性心脏病(简称冠心病)经皮冠状动脉介入术(PCI)术后的严重并发症,早期识别MACEs中、高风险人群,积极控制危险因素,对改善患者预后具有重要的临床意义.心血管疾病风险评估临床预测模型可识别心血管疾病风险,是临床医生开展健康教育和高危人群健康管理的重要工具.中医证素与PCI术后多种病理生理改变密切相关,基于证素构建PCI术后MACEs风险预测模型或有助于提高模型预测的准确性和特异性.通过纳入人群证素信息并采用队列研究数据进行拟合,构建中西医结合预测模型,综合评估同类模型应用效能的优劣性,并在实际应用中进行反复验证和不断优化,形成具有临床实用价值的评分体系与诊疗程式,有助于辅助PCI术后临床决策,优化临床管理.
Establishment of Risk Prediction Model of Coronary Heart Disease After Percutaneous Coronary Intervention Based on Chinese Medicine Syndrome Elements
Major adverse cardiovascular events(MACEs)are serious complications of coronary heart disease(CHD)patients after percutaneous coronary intervention(PCI).Early identification of middle-risk and high-risk individuals with MACEs and active control of risk factors have important clinical significance for improving prognosis.The clinical prediction model of cardiovascular disease risk assessment can identify the risk of cardiovascular disease,which is an important tool for clinicians to carry out health education and health management of high-risk populations.Chinese medicine(CM)syndrome elements are closely related to various pathophysiological changes after PCI,and the construction of a risk prediction model for MACEs after PCI based on syndrome elements may help to improve the accuracy and specificity of the model prediction.The integrated Chinese and Western medicine clinical prediction model can be constructed by incorporating the information of the population and fitting the data from the cohort study.The advantages and disadvantages of similar models were comprehensively evaluated,and repeated validation and optimization were carried out in practical applications to form a scoring system and diagnostic and therapeutic procedures with clinical utility,which can help to assist clinical decision-making and optimize clinical management of the post-PCI.

coronary atherosclerotic heart diseasepercutaneous coronary interventionclinical risk prediction modelmajor adverse cardiovascular eventssyndrome elementChinese medicineintegrative medicine

陶诗怡、于林童、李军、杨德爽、黄炫淳、张兰鑫、邵明晶、黄力

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北京中医药大学研究生院(北京 100029)

中国中医科学院广安门医院心血管科(北京 100053)

中日友好医院中西医结合心脏内科(北京 100029)

中国中医科学院广安门医院肿瘤科(北京 100053)

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冠状动脉粥样硬化性心脏病 经皮冠状动脉介入术 临床风险预测模型 主要不良心血管事件 证素 中医 中西医结合

2024

中国中西医结合杂志
中国中西医结合学会 中国中医科学院

中国中西医结合杂志

CSTPCD北大核心
影响因子:2.149
ISSN:1003-5370
年,卷(期):2024.44(12)