Application analysis of comprehensive nursing mode combined with dexmedetomidine hydrochloride in critically ill patients undergoing mechanical ventilation in neurosurgery
Objective To analyze the clinical application effect of comprehensive nursing mode combined with dexmedetomidine hydrochloride in critically ill patients undergoing mechanical ventilation in neurosurgery.Methods Eighty-four critically ill patients with mechanical ventilation admitted to the Neurosurgery Intensive Care Unit of the Affiliated Wuxi People's Hospital of Nanjing Medical University from January 2021 to March 2023 were selected as the study subjects.All patients were treated with dexmedetomidine hydrochloride for sedation and divided into a control group and an observation group according to a simple random number table method.42 patients in the control group received routine intervention,while 42 patients in the observation group received comprehensive nursing mode on the basis of routine intervention.The arterial oxygen saturation(SpO2)level and mean arterial pressure(MAP)of the two groups were compared.Results The clinical indicators(sedative onset time,recovery time after discontinuation,etc.)and total incidence of adverse reactions in the observation group were better than those in the control group(all P<0.05).At 12 hours,24 hours,and 48 hours after sedation,the SpO2 levels in both groups were higher than those in the same group at 1 hour after sedation(all P<0.05),and were higher in the observation group than in the control group at the same time(all P<0.05).After 1 and 2 weeks of intervention,the heart rate and MAP of both groups were lower than before intervention in the same group(all P<0.05),and were lower in the observation group than in the control group at the same time(all P<0.05).Conclusion The comprehensive nursing mode combined with dexmedetomidine hydrochloride can improve the clinical indicators,SpO2 levels,heart rate,and MAP of critically ill patients undergoing mechanical ventilation,and reduce the incidence of adverse reactions.
万方数据
维普
