首页|Cordyceps as potential therapeutic agents for atherosclerosis
Cordyceps as potential therapeutic agents for atherosclerosis
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Atherosclerosis is a leading cause of mortality and morbidity worldwide.Despite the challenges in managing atherosclerosis,researchers continue to investigate new treatments and complementary ther-apies.Cordyceps is a traditional Chinese medicine that has recently gained attention as a potential ther-apeutic agent for atherosclerosis.Numerous studies have demonstrated the effectiveness of cordyceps in treating atherosclerosis through various pharmacological actions,including anti-inflammatory and antioxidant activities,lowering cholesterol,inhibiting platelet aggregation,and modulating apoptosis or autophagy in vascular endothelial cells.Notably,the current misuse of the terms cordyceps and Ophiocordyceps sinensis has caused confusion among researchers,and complicated the current academic research on cordyceps.This review focuses on the chemical composition,pharmacological actions,and underlying mechanisms contributing to the anti-atherosclerotic effects of cordyceps and the mycelium of Ophiocordyceps spp.This review provides a resource for the research on the development of new drugs for atherosclerosis from cordyceps.
AtherosclerosisCordycepsOphiocordyceps sinensis
Yi Zhang、Si-jing Liu
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School of Marxism,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan Province,China
College of Medical Technology,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan Province,China
Chongqing Key Laboratory of Sichuan-Chongqing Co-construction for Diagnosis and Treatment of Infectious Diseases with Integrated Chinese and Western Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan Province,China
四川省科技厅项目四川省科技厅项目the"Xinglin Scholar"Talent Research Promotion Plan of Chengdu University of Traditional Chinese Medicinethe"Xinglin Scholar"Talent Research Promotion Plan of Chengdu University of Traditional Chinese Medicine