首页|Chinese herbal medicine Ginkgo biloba L.preparations for ischemic stroke:An overview of systematic reviews and meta-analyses

Chinese herbal medicine Ginkgo biloba L.preparations for ischemic stroke:An overview of systematic reviews and meta-analyses

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Background:Ginkgo biloba L preparations(GBLPs)are a class of Chinese herbal medicine used in the adju-vant treatment of ischemic stroke(IS).Recently,several systematic reviews(SRs)and meta-analyses(MAs)of GBLPs for IS have been published.Objective:This overview aims to assess the quality of related SRs and MAs.Search strategy:PubMed,Embase,Cochrane Library,Web of Science,Chinese Biological Medicine,China National Knowledge Infrastructure,Wanfang,and Chinese Science and Technology Journals databases were searched from their inception to December 31,2022.Inclusion criteria:SRs and MAs of randomized controlled trials(RCTs)that explored the efficacy of GBLPs for patients with IS were included.Data extraction and analysis:Two independent reviewers extracted data and assessed the methodological quality,risk of bias(ROB),reporting quality,and credibility of evidence of the included SRs and MAs using A Measurement Tool to Assess Systematic Reviews 2(AMSTAR 2),Risk of Bias in Systematic Reviews(ROBIS),the Preferred Reporting Items for Systematic Reviews and Meta-analyses(PRISMA),and the Grading of Recommendations Assessment,Development and Evaluation(GRADE),respectively.Additionally,descriptive analysis and data synthesis were conducted.Results:Twenty-nine SRs/MAs involving 119 outcomes were included in this review.The overall method-ological quality of all SRs/MAs was critically low based on AMSTAR 2,and 28 had a high ROB based on the ROBIS.According to the PRISMA statement,the reporting items of the included SRs/MAs are relatively complete.The results based on GRADE showed that of the 119 outcomes,8 were rated as moderate qual-ity,24 as low quality,and 87 as very low quality.Based on the data synthesis,GBLPs used in conjunction with conventional treatment were superior to conventional treatment alone for decreasing neurological function scores.Conclusion:GBLPs can be considered a beneficial supplemental therapy for IS.However,because of the low quality of the existing evidence,high-quality RCTs and SRs/MAs are warranted to further evaluate the benefits of GBLPs for treating IS.

Ginkgo biloba L.preparationsIschemic strokeOverviewSystematic review

Tian-tian Meng、Ya-ping You、Min Li、Jian-bo Guo、Xin-bin Song、Jing-yi Ding、Xiao-long Xie、An-qi Li、Shang-jin Li、Xiang-jun Yin、Peng Wang、Zhe Wang、Bao-liang Wang、Qing-yong He

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Department of Cardiology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100032,China

Department of Rehabilitation,Dongfang Hospital,Beijing University of Chinese Medicine,Beijing 100071,China

School of Chemistry and Chemical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China

School of Chinese Medicine,the University of Hong Kong,Hong Kong,China

Graduate School,Henan University of Chinese Medicine,Zhengzhou 450008,Henan Province,China

Department of Acupuncture and Moxibustion,Dongzhimen Hospital,Beijing University of Chinese Medicine,Beijing 100010,China

School of Integrated Traditional Chinese and Western Medicine,Southwest Medical University,Luzhou 646000,Sichuan Province,China

School of Basic Medical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang Province,China

Department of Neurology,the First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou 450003,Henan Province,China

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Traditional Chinese Medicine Ancient Book Documents and Characteristic Technology Inheritance Project of the National AdminiResearch and Transformation Application of Clinical Characteristic Diagnosis and Treatment Techniques in the CapitalNational Famous Old TCM Experts Baoliang Wang Inheritance Studio Construction Program,State TCM Office Human Education Lette

GZY-KJS-2020-079Z221100007422081[2022]75

2024

结合医学学报(英文版)
上海市中西医结合学会,上海长海医院

结合医学学报(英文版)

CSTPCD
影响因子:0.711
ISSN:2095-4964
年,卷(期):2024.22(2)
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