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Advancements in nanotechnology for the delivery of phytochemicals

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Phytosomes(phytophospholipid complex)are dosage forms that have recently been introduced to increase the stability and therapeutic effect of herbal medicine.Currently,bioactive herbs and the phy-tochemicals they contain are considered to be the best remedies for chronic diseases.One promising approach to increase the efficacy of plant-based therapies is to improve the stability and bioavailability of their bio-active ingredients.Phytosomes employ phospholipids as their active ingredients,and use their amphiphilic properties to solubilize and protect herbal extracts.The unique properties of phospho-lipids in drug delivery and their use in herbal medicines to improve bioavailability results in significantly enhanced health benefits.The introduction of phytosome nanotechnology can alter and revolutionize the current state of drug delivery.The goal of this review is to explain the application of phytosomes,their future prospects in drug delivery,and their advantages over conventional formulations.

PhytochemicalBioavailabilityDrug delivery systemPhytosomePlant extracts

Divya Chauhan、Pavan K.Yadav、Nazneen Sultana、Arun Agarwal、Saurabh Verma、Manish K.Chourasia、Jiaur R.Gayen

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Division of Pharmaceutics and Pharmacokinetics,Central Drug Research Institute,Council of Scientific and Industrial Research,Lucknow 226031,Uttar Pradesh,India

Academy of Scientific and Innovative Research,Ghaziabad 201002,Uttar Pradesh,India

Department of Science and Technology,Government of India,for the Innovation in Science Pursuit for Inspired Research FellowsDr Radha Rangarajan,the director of CSIR-CDRI(CSIR-CDRI communication)

10772

2024

10.1016/j.joim.2024.04.005

结合医学学报(英文版)
上海市中西医结合学会,上海长海医院

结合医学学报(英文版)

CSTPCD
影响因子：0.711
ISSN：2095-4964
年,卷(期)：2024.22(4)