Abstract
Visnagin is a furanochromone and one of the most important compound in the Ammi visnaga(L.)Lam(a synonym of Visnaga daucoides Gaertn.)plant,which is used to cure various ailments.Many investigations into the bioactive properties of visnagin have been studied to date.The literature on visnagin demon-strates its biological properties,including anti-inflammatory,anti-diabetic,and beneficial effects in car-diovascular and renal diseases.Moreover,visnagin improves sperm quality parameters,stimulates steroidogenesis,and increases serum gonadotropins and testosterone levels,while decreasing pro-inflammatory cytokines,oxidative damage,genomic instability,and it modulates apoptosis.Thus,vis-nagin has emerged as an exciting lead for further research,owing to its potential in various unmet clinical needs.The current review summarized its basic structure,pharmacokinetics,and pharmacological effects,focusing on its mechanisms of action.The review will help to understand the potential of visnagin as an alternative treatment strategy for several diseases and provide insight into research topics that need further exploration for visnagin's safe clinical use.
基金项目
Indian Council of Medical Research,Government of India for providing Senior Research Fellowships(45/04/2022-PHA/BMS)
Indo-German Science and Technology Centre for providing the Paired Early Career Fellowship in Applied Research fellowship(IGSTC/PECFAR/Call 2022/US-AK/36/2022-23/Award letter/488)
国家科技期刊平台
NSTL
万方数据