Clinical Study on the Treatment of Osteoporotic Thoracolumbar Vertebral Compression Fractures with Bushen Huoxue Decoction
Objective To explore the clinical efficacy of Bushen Huoxue decoction in the treatment of osteopo-rotic thoracolumbar vertebral compression fractures.Methods A total of 120 patients with osteoporotic thoraco-lumbar vertebral compression fractures were randomly divided into the control group and the trial group,with 60 cases in each group.Both groups were treated with percutaneous vertebroplasty(PVP).The control group received postoperative treatment with alendronate sodium,while the trial group received additional treatment with Bushen Huoxue decoction.Both groups were treated for three months.The clinical total effective rate,bone density,anteri-or vertebral height,Cobb angle,vertebral function,pain scores,bone transformation indicators,and levels of blood calcium and phosphorus in the two groups were compared.Results After treatment,there was no statistically sig-nificant difference in the total effective rate between the two groups(P>0.05).The bone density,anterior verte-bral height,osteocalcin(OC),osteoprotegerin(OPG)and blood phosphorus in the trial group were all higher than those in the control group(all P<0.05).Cobb angle,Oswestry disability index(ODI)and visual analogue scale(VAS)scores,bone alkaline phosphatase(BALP)and blood calcium in the trial group were all lower than those in the control group(all P<0.05).Conclusion The application of Bushen Huoxue decoction in the treatment of os-teoporotic thoracolumbar vertebral compression fractures could restore vertebral height,increase bone density,im-prove vertebral mobility,alleviate pain,and effectively regulate bone metabolism index levels,which is worthy of promotion.