Clinical Study on the Treatment of Recurrent Spontaneous Abortion with Zishen Yutai Pill
Objective To explore the clinical efficacy of Zishen Yutai pill in the treatment of recurrent sponta-neous abortion.Methods Eighty-four early pregnant women with a history of recurrent spontaneous abortion were selected and randomly divided into the treatment group and the control group using a random number table meth-od,with 42 cases in each group.The control group received routine symptomatic supportive treatment,while the treatment group received an additional treatment of Zishen Yutai pill on the basis of the control group.Both groups continued to take the medication until 12+6 weeks of pregnancy.The levels of serum progesterone(P)and human chorionic gonadotropin(hCG),as well as coagulation related indicators such as platelet count and D-dimer were compared in the two groups.And the success rate of maintaining pregnancy and the duration of pregnancy were al-so compared.Results After treatment,the levels of hCG in both groups increased compared to those before treat-men(all P＜0.05),and the hCG of the treatment group were significantly higher than that of the control group(P＜0.05).The comparison of serum P,platelet count and D-dimer before and after treatment,as well as between the two groups were no statistically significant difference(P＞0.05).Follow up to 12+6 weeks of pregnancy,the success rate in the control group was 61.90％(26/42),while the treatment group was 71.43％(30/42).There was no statistically significant difference in the success rate of maintaining pregnancy between the two groups(P＞0.05).Conclusion The combination of conventional tocolytic therapy and Zishen Yutai pill in the treatment of re-current spontaneous abortion had a trend of promoting pregnancy and improving the success rate of fetal preserva-tion,but further research is needed.
万方数据
维普
