Effect of Gejiu Bushen Qianggu Decoction on Bone Mineral Density and Bone Metabolism Indicators in Elderly Osteoporosis
Objective To observe the effect of Gejiu Bushen Qianggu decoction on bone mineral density(BMD)and bone metabolism indicators in elderly patients with osteoporosis(OP).Methods Sixty OP patients who re-ceived treatment in our hospital from October 2022 to October 2023 were selected and randomly divided into a treatment group and a control group using a random number table method,with 30 patients in each group.The con-trol group was treated with conventional calcium supplementation and promotion of calcium absorption treatment,while the treatment group was treated with Gejiu Bushen Qianggu decoction on the basis of treatment in the con-trol group.Both groups of patients were treated for 12 weeks.The levels of BMD,serum alkaline phosphatase(ALP),calcium(Ca),procollagen type Ⅰ N-prepeptide(PⅠNP),β-crosslaps(β-CTX),bone glaprotein(BGP),and traditional Chinese medicine syndrome scores before and after treatment were compared between the two groups,and the clinical efficacy of two groups of patients was compared.Results After 12 weeks of treatment,the levels of BMD,serum BGP,Ca,and PⅠNP in the treatment group were significantly higher than those in the control group(P＜0.05).The TCM syndrome score and serum levels of ALP,β-CTX in the treatment group were significantly lower than those in the control group(P＜0.05).The total effective rate of the treatment group was significantly higher than that of the control group(P＜0.05).Conclusion Gejiu Bushen Qianggu decoction could improve the bone metabolism status of osteoporosis patients,increase BMD levels,alleviate clinical symptoms,and has signifi-cant clinical efficacy.
Gejiu Bushen Qianggu decoctionosteoporosisbone metabolismbone mineral density
万方数据
维普
