Efficacy of Chuipencao Granules Combined with Valacyclovir in the Treatment of Herpes Zoster and its Effect on Serum Inflammatory Factors
Objective To investigate the clinical efficacy of Chuipencao granules combined with valacyclovir in the treatment of herpes zoster.Methods Ninety-four patients with herpes zoster treated at our community health service center from January 2022 to January 2024 were selected and randomly divided into the control group and the observation group according to the random number table method,with 47 cases in each group.The control group was treated with valacyclovir,while the observation group was treated with Chuipencao granules combined with va-lacyclovir.The area of skin lesions,visual analogue scale(VAS)score,number of herpes,serum inflammatory factor levels,and treatment safety between two groups of patients were compared.Results After treatment,the area of skin lesions,VAS scores and number of herpes in the observation group were significantly lower than those in the control group(P＜0.05).The serum levels of interleukin(IL)-1β,tumor necrosis factor(TNF)-α and IL-6 in the observation group were significantly lower than those in the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups of patients(P＞0.05).Conclusion Chuipencao granules combined with valacyclovir in the treatment of herpes zoster patients could promote symptom improve-ment,reduce levels of inflammatory factors,and has good safety.
万方数据
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