Objective Epidemiological investigation was conducted on an outbreak of diarrhea infected by non-O1 and non-O139 group Vibrio cholerae,to explore the causes and to provide reference for preventing similar incidents.Methods An investigation was conducted on an outbreak of diarrhea infected by non-01 and non-O139 group Vibrio cholerae in a college of Provincial Vocational Education City in Qingcheng district of Qingyuan City in September 2020.Epidemiological methods were used to investigate the clinical manifestations and distribution of cases,explore risk factors,and collect relevant samples for laboratory testing.SPSS 23.0 was used for statistical analysis.The comparison of inter group rates was conducted by using Chi-square test,and the test level was α=0.05.Results A total of 130 cases were reported in this incident,with a total incidence rate of 2.76％(130/4 710).Among them,there were 8 teachers,with an incidence rate of 5.03％(8/159);121 students,with an incidence rate of 2.81％(121/4 306);One manager of cafeteria,with an incidence rate of 0.94％(1/106).There was no statistically significant difference in the incidence rate among the three groups of people(x2=4.17,P=0.101).The clinical manifestations include diarrhea(97.69％),abdominal pain(62.30％),fever(11.54％),vomiting(7.69％),and nausea(6.92％).The anal swab,environment of kitchen,drinking water and other samples of the case all detected Vibrio cholerae,which was identified as non-O1 and non-O139 serotypes.Conclusions After investigation,it is believed that this is an outbreak of non-O1 and non-O139 Vibrio cholerae infectious diarrhea caused by contaminated drinking water.Targeted measures should be taken to prevent similar incidents from occurring.
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