中医眼耳鼻喉杂志2024,Vol.14Issue(3) :149-151,161.DOI:10.3969/j.issn.1674-9006.2024.03.009

瞬时受体电位离子通道在糖尿病视网膜病变中的研究进展

Research progress of transient receptor potential ion channels in diabetic retinopathy

程雨欣 路雪婧
中医眼耳鼻喉杂志2024,Vol.14Issue(3) :149-151,161.DOI:10.3969/j.issn.1674-9006.2024.03.009

瞬时受体电位离子通道在糖尿病视网膜病变中的研究进展

Research progress of transient receptor potential ion channels in diabetic retinopathy

程雨欣 1路雪婧1
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作者信息

  • 1. 610075,四川成都,成都中医药大学眼科学院;610075,四川成都,中医药眼病防治与视功能保护四川省重点实验室
  • 折叠

摘要

糖尿病视网膜病变的发生涉及到视网膜血管结构的改变,同时也与血管周围神经元或神经胶质组织的功能障碍有关,瞬时受体电位(transient receptor potential,TRP)离子通道是一类功能多样、广泛分布的阳离子通道超家族,近年来的研究表明了 TRP通道在糖尿病视网膜病变的发病机制中发挥重要作用.本文总结了近年来关于TRP通道在糖尿病视网膜病变发病机制及相关研究的最新进展,目的是为糖尿病视网膜病变的治疗提供更广泛的研究视角和方向.

Abstract

Diabetic retinopathy,a complication of diabetes,involves structural changes in retinal blood vessels and dysfunction of surrounding neurons or glial tissue.Transient receptor potential(TRP)ion channels,a diverse and widely distributed superfamily of cation channels,have been implicated in the pathogenesis of diabetic retinopathy.Recent studies have highlighted the significant role of TRP channels in the development of diabetic retinopathy.This article summarizes the latest progress in understanding the involvement of TRP channels in the pathogenesis of diabetic retinopathy and relat-ed research,with the aim of providing a broader research perspective and direction for the treatment of diabetic retinopa-thy.

关键词

瞬时电位离子通道/糖尿病视网膜病变/发病机制

Key words

Transient receptor potential ion channels/Diabetic retinopathy/Pathogenesis

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基金项目

国家自然科学基金面上项目(82174444)

出版年

2024
中医眼耳鼻喉杂志
成都中医药大学

中医眼耳鼻喉杂志

ISSN:1674-9006
参考文献量34
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