动脉粥样硬化（atherosclerosis，AS）是动脉的慢性退化和动脉壁逐渐变化的过程，炎症贯穿于病变发生和发展的全过程。目前 AS 的研究主要集中于炎症细胞、炎性介质及免疫机制的相互作用方面。大量研究显示，天然药物对 AS 中炎症反应有明显的调节作用。本文对炎症的触发机制、AS 初期、AS 中炎症发展与并发症三个方面以及涉及的天然药物对 AS 治疗的相关研究进行总结，以期为今后天然药物对 AS 中炎症的调控及机理研究提供参考。
Recent Advances in Regulation of Natural Medicine on Inflammation in Atherosclerosis
Atherosclerosis (AS)is a chronic process of gradual degradation and changes in arteries.Inflammation is involved in the entire development process of atherosclerosis.Currently,researches of AS focus on the interaction of inflammatory cells,inflammatory mediators and immune mechanisms.A large number of studies have shown that natural medicine play a regulatory role on inflammation in AS.This review summarizes triggers for inflammation,initiation of the AS and inflammation in atheroma progression and complication,as well as researches involved in treatment of AS with natural medicine.This article may provide some theoretical basis for future researches on regulation and the mechanism of natural medicine treatment for inflammation in AS.
国家科技期刊平台
NSTL
万方数据
维普
