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草珊瑚属药用植物的生物活性物质基础

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评述金粟兰科草珊瑚属药用植物草珊瑚和海南草珊瑚的化学成分和分析方法、生物学活性和药理学作用、安全性、临床应用.尽管已从草珊瑚属药用植物中分离鉴定出三萜、苯丙素、香豆素、木脂素、黄酮、酚、酚酸等类型化合物,但倍半萜类化合物无论是在含量上,还是在化学结构多样性上,占绝对优势地位,它们可能是草珊瑚属药用植物的重要生物活性物质基础之一.
Bioactive Material Basis of Medicinal Plants in Genre Sarcandra
Sarcandra glabra(Thunb.) Nakai subsp.glabra and S.glabra(Thunb.) Nakai subsp.brachystachys(Blume) Verdc.[=S.hainanensis (C.Pei) Swamy et I.W.Bailey] are medicinal herbs in the Chloranthaceae family.In this article,the studies on chemical constituents and their analytical methods,biological and pharmacological activities,safety assessments,and clinical uses were reviewed.Even though triterpenoids,phenylpropanoids,coumarins,lignanoids,flavonoids,phenolics,phenolic acids and sesquiterpenoids were isolated and determinated,sesquiterpenoid compounds are predominantly dominant type not only in amount but also in structural varieties,which should be one of important bioactive material basis of medicinal plants in genus Sarcandra.

Sarcandra glabraSarcandra glabra ssp.brachystachysbioactive material basissesquiterpene

杨秀伟

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北京大学天然药物及仿生药物国家重点实验室,北京大学药学院天然药物学系,北京100191

草珊瑚 海南草珊瑚 生物活性物质基础 倍半萜

“十二五”国家科技支撑项目

2011BAI07B08

2017

中国现代中药
中国中药协会,中国医药集团总公司,中国药材公司

中国现代中药

CSTPCD
影响因子:0.65
ISSN:1673-4890
年,卷(期):2017.19(2)
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