Optimization of Extraction Process of Wenfei Pingchuan Decoction Based on Analytic Hierarchy Process and Entropy Weight Method
Objective:The analytic hierarchy process(AHP)and entropy weight method(EWM)was used to establish a multi-index comprehensive evaluation method to optimize the extraction process of Wenfei Pingchuan Decoction.Methods:The content of paeoniflorin,liquiritin,rosmarinic acid,salvianolic acid B,glycyrrhizic acid and the yield of dry extract were used as evaluation indexes.The weight coefficient was determined by AHP and EWM.L9(34)orthogonal design was used to investigate the effects of water addition,extraction time and number of extractions on the extraction process of Wenfei Pingchuan Decoction.Results:The optimal extraction process was to extract 3 times with 8 times amount of waterfor 1 h each time.Conclusion:The optimized extraction condition has good repeatability,stability and high extraction rate,which is suitable for the standardized production of Wenfei Pingchuan Decoction.
Wenfei Pingchuan Decoctionextraction processanalytic hierarchy process and entropy weight methodsalvianolic acid B
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