Historical Evolution of Classical Prescription Zhujing Pill and Analysis of Its Prescription Information
Zhujing Pill is the 40th Chinese medicine of the Han ethnic group included in the Catalogue of Ancient Classic Famous Prescriptions(the Second Batch)[Gu Dai Jing Dian Ming Fang Mu Lu(Di Er Pi)]in 2023.It originates from the Taiping Holy Prescriptions for Universal Relief(Tai Ping Sheng Hui Fang)in the Northern Song Dynasty,and is composed of Semen Cuscutae,Semen Plantaginis and Radix Rhemanniae Praeparata,with the efficacy of tonifying and nourishing liver and kidney,clearing heat,and improving vision.Zhujing Pill is a famous prescription commonly used in ophthalmology of traditional Chinese medicine(TCM)for mainly treating eye diseases of liver and kidney deficiency.Ancient and modern literature on Zhujing Pill was collected and analyzed by bibliometrics,and 63 pieces of valid data were screened out from ancient books,involving 47 ancient TCM books.This paper conducted a systematic sorting of the historical origin,prescription names,composition and dosage,herb origin and processing,preparation and usage,therapeutic efficacy,and other aspects of Zhujing Pill,and summarized its key information.The results showed that the ratio of Semen Cuscutae,Semen Plantaginis and Radix Rhemanniae Praeparata in Zhujing Pill was 5∶3∶3,which followed the dosage in the Formulary of the Bureau of Taiping People's Welfare Pharmacy(Tai Ping Hui Min He Ji Ju Fang).Modified Zhujing Pill was first recorded in the Li Jushi's Prescriptions(Li Ju Shi Jian Yi Fang Lun),and its indications were similar to those of the original prescription,but with more comprehensive and powerful efficacy,and it was more frequently applied in the past.Modern physicians continued to update Zhujing Pill,and put forward derivative prescriptions such as Zhujing Jiajian Pill and Tongluo Zhujing Pill.They have been widely used in ophthalmology and achieved good curative effect.Zhujing prescriptions were based on tonifying and nourishing liver and kidney,concurrently calming heart and tranquilizing mind,or clearing heat and removing dampness,or dispersing blood stasis and unblocking meridian.However,the pathogenesis lied in liver and kidney deficiency,which caused blurred vision.Zhujing prescriptions had excellent application prospects for age-related eye disease,senile degenerative changes,and myopia of juvenile.Relevant pharmacological studies and the development of Chinese medicine preparations could be carried out in the future.
classical prescriptionZhujing PillTaiping Holy Prescriptions for Universal Relief(Tai Ping Sheng Hui Fang)historical evolutionprescription informationliterature research
国家科技期刊平台
NSTL
万方数据
