首页|多指标结合AHP-CRITIC优化酸枣叶拌蒸酸枣仁炮制工艺

多指标结合AHP-CRITIC优化酸枣叶拌蒸酸枣仁炮制工艺

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目的:采用正交设计结合层次分析法-客观赋权法(AHP-CRITIC)优化酸枣叶拌蒸酸枣仁的炮制工艺.方法:采用单因素试验优化辅料酸枣叶的加入倍量和蒸制时间,以酸枣叶的加入倍量和蒸制时间为因素,以斯皮诺素、6‴-阿魏酰斯皮诺素、酸枣仁皂苷A、白桦脂酸含量为评价指标进行综合加权评分,结合AHP-CRITIC优化酸枣仁的拌蒸工艺.结果:最佳拌蒸工艺为酸枣叶加入量是酸枣仁的4倍,1层酸枣叶1层酸枣仁交替平铺,上锅蒸制3 h.结论:多指标结合AHP-CRITIC优选酸枣仁拌蒸工艺合理可行,可为酸枣叶拌蒸酸枣仁炮制工艺的生产实践提供参考.
Optimization of the Co-steaming Process of Semen Ziziphi Spinosae with Ziziphus Jujuba Leaf by Multi-index Combined with AHP-CRITIC Method
Objective:To optimize the co-steaming process of Semen ziziphi spinosae with Ziziphus jujuba leaf based on orthogonal design and AHP-CRITIC method.Method:The single-factor experiment was applied to screen dosage range for Z.jujuba leaf and steaming time.Then,the co-steaming process was optimized by orthogonal design combined with AHP-CRITIC method with the contents of spinosin,6‴-ferulospinosin,jujuboside A,and betulinic acid as evaluation indexes and usage amount of Z.jujuba leaf and steaming time as influencing factors.Results:The optimal co-steaming process was to lay the Z.jujuba leaf and Semen ziziphi spinosae alternately,and the usage amount for Z.jujuba leaf was four times that of Semen ziziphi spinosae.The steaming time was 3 hours.Conclusion:The orthogonal design combined with AHP-CRITIC method was reasonable and feasible,and could provide a reference for the production practice of co-steaming process of Semen ziziphi spinosae with Z.jujuba leaf.

Semen ziziphi spinosaeZiziphus jujuba leafco-steaming processorthogonal designAHP-CRITIC

程世赞、华悦、廉婧、聂紫璇、苏国明、常源、史辑、贾天柱

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辽宁中医药大学 药学院,辽宁 大连 116600

辽宁省中药炮制技术产业创新中心,辽宁 大连 116600

酸枣仁 酸枣叶 拌蒸工艺 正交设计 层次分析法-客观赋权法

国家自然科学基金国家中医药局重点实验室研究领域的中医临床疗效提升项目沈阳市中青年科技创新人才支持计划辽宁省自然科学基金面上项目(2022)

818743452100222179RC2001742022-MS-223

2024

中国现代中药
中国中药协会,中国医药集团总公司,中国药材公司

中国现代中药

CSTPCD
影响因子:0.65
ISSN:1673-4890
年,卷(期):2024.26(4)
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