Effect of Gypsum Decocting Process on Physicochemical Properties of the Microparticle System of Qingfei Paidu Decoction
Objective:To study the effect of gypsum decocting process on the physicochemical properties of the microparticle system of Qingfei Paidu Decoction.Methods:The water decoction and formula granule preparation solution of Qingfei Paidu Decoction were prepared by different decoction methods of gypsum(direct decoction,pre-decoction,wrap-decoction and separate decoction).The solid particles in each water decoction and formula granule preparation solution were separated by gradient centrifugation at centrifugal forces of 830×g,3300×g and 13 200×g,respectively,and the particle size,potential,morphology,element composition,protein and polysaccharide contents were analyzed.Results:The particle size of the microparticles in each decoction groups and formula granule groups was decreased with the increase of centrifugal force,and the particle size of decoction groups was larger than that of granule groups.The potential of microparticles in each water decoction and formula granule groups was always negative,and there was no significant difference among the groups.The preparation method of water decoction and decocting method of gypsum significantly affected the morphology of the microparticles of Qingfei Paidu Decoction:the microparticles in gypsum direct decoction and separate decoction groups(water decoction)showed spherical and ellipsoidal shapes with different sizes,in which flaky and fibrous substances were observed;the microparticles in gypsum pre-decoction and wrap-decoction groups(water decoction)showed reticular structure;the microparticles in formula granule groups were accumulated as irregular bulk.The element composition of microparticles in each group is C,O and Ca,and the polysaccharide content was higher than that of protein.However,the content of polysaccharide in the water decoction groups was lower than that in the formula granule preparation solution groups.Conclusion:The particle size,potential,morphology,element composition,protein and polysaccharide contents of Qingfei Paidu Decoction prepared by"Co-decocting"method were different from those of the formula granule preparation solution,and the decocting process of gypsum also affected the physicochemical properties and physical forms of microparticles in water decoction groups.
国家科技期刊平台
NSTL
万方数据
维普
