中国现代中药2024,Vol.26Issue(4) :733-748.DOI:10.13313/j.issn.1673-4890.20231221001

补骨脂化学成分研究进展

Research Progress in Chemical Constituents of Psoraleae Fructus

杨秀伟 许青霞 吕倩 和子超 徐嵬 张英涛
中国现代中药2024,Vol.26Issue(4) :733-748.DOI:10.13313/j.issn.1673-4890.20231221001

补骨脂化学成分研究进展

Research Progress in Chemical Constituents of Psoraleae Fructus

杨秀伟 1许青霞 1吕倩 1和子超 1徐嵬 1张英涛1
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作者信息

  • 1. 北京大学 药学院 天然药物学系/天然药物及仿生药物全国重点实验室,北京 100191
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摘要

补骨脂是豆科植物Psoralea corylifolia L.的干燥成熟果实,作为一种传统的中药,其在我国已有几千年的临床应用历史,广泛地用于心血管疾病、肾炎、骨质疏松和癌症等的治疗.植物化学研究显示,香豆素类、杂萜类和黄酮类是其主要化学成分.对补骨脂化学成分研究进行系统梳理,以期为临床更安全、有效地使用补骨脂和研究补骨脂现代中药提供理论依据.

Abstract

Psoraleae Fructus,the dried mature fruit of Psoralea corylifolia L.,is a Chinese herbal medicine that has been used in clinical practice for thousands of years.It has been widely used in Chinese medicine formulas for treating cardiovascular diseases,nephritis,osteoporosis,and cancers.Phytochemical studies have demonstrated that coumarins,terpenoids,and flavonoids are the main constituents of Psoraleae Fructus.This paper systematically reviews the studies about the chemical constituents of Psoraleae Fructus,aiming to provide a theoretical basis for the safe and effective application of Psoraleae Fructus in clinical practice and the modern medical research and development of this medicine.

关键词

补骨脂/化学成分/香豆素类/杂萜类/黄酮类

Key words

Psoralea corylifolia L./chemical constituents/coumarins/terpenoids/flavonoids

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基金项目

国家自然科学基金(81773865)

出版年

2024
中国现代中药
中国中药协会,中国医药集团总公司,中国药材公司

中国现代中药

CSTPCD
影响因子:0.65
ISSN:1673-4890
参考文献量81
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