Research Progress on Chemical Components and Pharmacological Effects of Tibetan Medicine Lamiophlomis rotata and Its Quality Marker Prediction Analysis
Lamiophlomis rotata(Benth.)Kudo is a traditional Tibetan medicine,and the medicinal part is the dry aerial part.Modern studies have shown that L.rotata mainly contains iridoid glycosides,phenylethanoid glycosides,flavonoids,volatile oil and other chemical components.It has analgesic,hemostatic,antibacterial,anti-inflammatory,immunomodulatory,and antitumor pharmacological effects.On the basis of summarizing the chemical components and pharmacological effects of L.rotata,combined with its quality research status,the quality marker(Q-marker)was predicted from the aspects of medicinal properties,efficacy,component measurability and pharmacokinetics.Quercetin,apigenin,shanzhiside methyl ester,8-O-acetylshanzhiside methyl ester,sesamoside,forsythiaside B,luteoloside,loganin and other components can be used as the main Q-marker of L.rotata,so as to provide a reference for the development and research of L.rotata products and the reasonable establishment of quality standards.