Research Progress and Q-marker Prediction Analysis of Traditional Chinese Medicine Polygonum cuspidatum
Polygonum cuspidatum(P.cuspidatum)is a commonly used bulk traditional Chinese medicine(TCM)in China,with rich resources and wide distribution,and has broad prospects for development and utilization.P.cuspidatum has a wide range of chemical components,including stilbenes,anthraquinones,flavonoids and other compounds.The pharmacological effects of P.cuspidatum are mainly anti-inflammatory,antioxidant,antiviral,antibacterial,anticancer effects,liver protection,cardiovascular protection,immune regulation and so on.Based on the summary of its chemical components and pharmacological effects,and the theory of quality marker(Q-marker)of TCM,the Q-marker components of P.cuspidatum were predicted and analyzed from the aspects of the source of TCM,chemical component effectiveness,chemical component detectability and different compatibility environments,so as to provide a basis for clarifying the Q-marker of P.cuspidatum and formulating scientific quality standards.
Polygonum cuspidatum Sieb.et Zucc.Q-markersanthraquinonesstilbenesquality control