中国现代中药2024,Vol.26Issue(5) :927-936.DOI:10.13313/j.issn.1673-4890.20231106001

丹参-三七药对治疗冠心病的药效和机制研究进展

Research Progress on Pharmacological Effects and Mechanisms of Salvia miltiorrhiza-Panax notoginseng Herb Pair on Coronary Heart Disease

陶慧娟 王文晓 乐世俊
中国现代中药2024,Vol.26Issue(5) :927-936.DOI:10.13313/j.issn.1673-4890.20231106001

丹参-三七药对治疗冠心病的药效和机制研究进展

Research Progress on Pharmacological Effects and Mechanisms of Salvia miltiorrhiza-Panax notoginseng Herb Pair on Coronary Heart Disease

陶慧娟 1王文晓 2乐世俊2
扫码查看

作者信息

  • 1. 南京市第二医院 药学部,江苏 南京 210003
  • 2. 河北中医药大学 河北省中药资源利用与质量评价国际联合研究中心,河北 石家庄 050200
  • 折叠

摘要

近些年来,丹参和三七在临床上常被用来治疗冠心病如心肌缺血、动脉粥样硬化,以及与冠心病等危的糖尿病和高血压等.因此,丹参-三七药对及其组分配伍治疗冠心病的潜在机制受到广泛关注.大量文献表明丹参-三七及其组分配伍在治疗冠心病中具有调节脂质代谢和能量代谢、抗炎、抗血小板聚集、改善内皮细胞功能作用.总结了丹参-三七药对及其组分配伍在治疗冠心病中的药效和机制,以期为其后续研究提供更全面的理论依据.

Abstract

In recent years,Salvia Miltiorrhiza and Panax notoginseng are often used clinically to treat coronary heart disease such as myocardial ischemia,atherosclerosis,as well as diabetes and hypertension which are the same health threatening as coronary heart disease.Therefore,the potential mechanism of their herb pair(DQ)and its component compatibility to treat coronary heart disease has received extensive attention.Numerous literature have revealed that DQ and its component compatibility have the effects of regulating lipid metabolism and energy metabolism,anti-inflammatory,anti-platelet aggregation and improving endothelial cell function in the treatment of coronary heart disease.This paper summarized the pharmacological effects and mechanisms of DQ and its component compatibility,so as to provide a comprehensively theoretical basis for subsequent research of DQ.

关键词

丹参/三七/组分配伍/冠心病

Key words

Salvia miltiorrhiza Bge./Panax notoginseng(Burk.)F.H.Chen/component compatibility/coronary heart disease

引用本文复制引用

基金项目

国家自然科学基金青年科学基金(81903786)

陕西中医药大学校级科研项目(2023GP24)

出版年

2024
中国现代中药
中国中药协会,中国医药集团总公司,中国药材公司

中国现代中药

CSTPCD
影响因子:0.65
ISSN:1673-4890
参考文献量68
段落导航相关论文