Ampelopsis Michaux is a genus of perennial woody vine encompassing roughly 30 species globally,of which approximately 17 are found in China,with the majority being endemic.Historically,most species of this genus have been revered for their medicinal properties,extensively consumed as therapeutic tea beverages across various ethnic groups.Recent taxonomical assessments,underpinned by phylogenetic relationships and morphological criteria,have led to the delineation of the species possessing pinnate compound leaves from Ampelopsis,subsequently categorizing them into a new genus termed Nekemias.Yet,corroborative evidence,particularly from phytochemical analyses,remains paramount.This study delves into the genetic affinities,chemical profiles,and pharmacological properties of Ampelopsis.Notably,while the plants of this genus are prolific in flavonoids,different species showcase distinct chemical constituents.For instance,those with pinnate compound leaves predominantly contain flavonoids such as dihydromyricetin and myricetin,whereas other species have phenolic acids like resveratrol and catechin.These chemical compounds demonstrate anti-tumor,hepatoprotective,and antimicrobial activities,resonating with traditional medicinal uses.Probing into the pharmacophylogenetic relationship of Ampelopsis helps to pave the way for conservation and therapeutic potential enhancement of plants belonging to this genus.
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