Influencing factors of neurological function recovery after interventional treatment of ruptured intracranial aneurysms
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目的 分析颅内破裂动脉瘤介入术后影响神经功能恢复的相关因素。 方法 前瞻性研究。抽取2021年9月至2023年6月于河南省人民医院接受颅内破裂动脉瘤介入术治疗的104例患者作为研究对象，术后随访6个月，根据改良Rankin评分量表(mRS)将患者分为神经功能恢复不良组与神经功能恢复良好组。设计基线资料调查表，纳入所有可能影响颅内破裂动脉瘤介入术后患者神经功能恢复的因素，使用单因素、Logistic回归分析颅内破裂动脉瘤介入术后神经功能恢复的影响因素。 结果 研究期间1例未完成手术，3例退出研究，最终研究样本量为100例，其中神经功能恢复不良14例，占比14.00%(14/100)；神经功能恢复良好86例，占比86.00%(86/100)。两组高血压、动脉瘤长径、吸烟史、合并并发症、Hunt-Hess分级、手术时机比较，差异有统计学意义(P<0.05)；Logistic回归分析结果显示，有高血压、动脉瘤长径大、有吸烟史、合并并发症、Hunt-Hess分级高、手术时机为晚期是影响颅内破裂动脉瘤介入术后神经功能恢复的危险因素(OR>1，P<0.05)。 结论 有高血压、动脉瘤长径大、有吸烟史、合并并发症、Hunt-Hess分级高、手术时机为晚期是影响颅内破裂动脉瘤介入术后神经功能恢复的危险因素。 Objective To analyze the related factors affecting the recovery of neurological function after interventional treatment of ruptured intracranial aneurysms. Methods In this prospective study, 104 patients with ruptured intracranial aneurysms who received interventional therapy in Henan Provincial People’s Hospital from September 2021 to June 2023 were selected as research subjects. The patients were followed up for 6 months. According to the modified Rankin rating scale (MRS), they were divided into the poor recovery group and the good recovery group. The baseline data questionnaire was designed to include all factors that may affect the recovery of neurological function of patients with ruptured intracranial aneurysms after interventional therapy. Univariate and logistic regression analyses were used to analyze the influencing factors of neurological function recovery after interventional therapy for ruptured intracranial aneurysms. Results During the study period, 1 case did not complete the operation, 3 cases withdrew from the study, and the final sample size was 100 cases, including 14 cases with poor neurological function recovery, accounting for 14.00% (14/100), and 86 cases with good neurological function recovery, accounting for 86.00% (86/100). There were significant differences in hypertension, aneurysm major diameter, smoking history, complications, Hunt-Hess classification and operation time between the two groups (P<0.05). The results of logistic regression analysis showed that hypertension, aneurysm major diameter, smoking history, complications, Hunt-Hess classification and operation time were the risk factors affecting the recovery of neurological function after interventional therapy for ruptured intracranial aneurysms (OR>1,P<0.05). Conclusions Hypertension, aneurysm major diameter, smoking history, complications, high Hunt-Hess classification and late operation time are the risk factors affecting the recovery of neurological function after interventional therapy for ruptured intracranial aneurysms.
Objective To analyze the related factors affecting the recovery of neurological function after interventional treatment of ruptured intracranial aneurysms. Methods In this prospective study, 104 patients with ruptured intracranial aneurysms who received interventional therapy in Henan Provincial People’s Hospital from September 2021 to June 2023 were selected as research subjects. The patients were followed up for 6 months. According to the modified Rankin rating scale (MRS), they were divided into the poor recovery group and the good recovery group. The baseline data questionnaire was designed to include all factors that may affect the recovery of neurological function of patients with ruptured intracranial aneurysms after interventional therapy. Univariate and logistic regression analyses were used to analyze the influencing factors of neurological function recovery after interventional therapy for ruptured intracranial aneurysms. Results During the study period, 1 case did not complete the operation, 3 cases withdrew from the study, and the final sample size was 100 cases, including 14 cases with poor neurological function recovery, accounting for 14.00% (14/100), and 86 cases with good neurological function recovery, accounting for 86.00% (86/100). There were significant differences in hypertension, aneurysm major diameter, smoking history, complications, Hunt-Hess classification and operation time between the two groups (P<0.05). The results of logistic regression analysis showed that hypertension, aneurysm major diameter, smoking history, complications, Hunt-Hess classification and operation time were the risk factors affecting the recovery of neurological function after interventional therapy for ruptured intracranial aneurysms (OR>1,P<0.05). Conclusions Hypertension, aneurysm major diameter, smoking history, complications, high Hunt-Hess classification and late operation time are the risk factors affecting the recovery of neurological function after interventional therapy for ruptured intracranial aneurysms.
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