Application value of18F-FDG PET/CT in staging diagnosis of elderly esophageal cancer
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目的 分析18氟-氟代脱氧葡萄糖正电子发射计算机断层扫描(18F-FDG PET/CT)在老年食管癌分期诊断中的应用价值。 方法 观察性研究。抽取2019年4月至2022年8月南阳市中心医院收治的老年食管癌患者69例，均行常规CT和18F-FDG PET/CT诊断，以病理结果为"金标准"，比较18F-FDG PET/CT和CT诊断TNM分期的诊断结果和诊断效能(灵敏度、特异度、准确度)。 结果 69例老年食管癌患者，病理结果显示T分期21例，N分期27例，M分期21例。CT和18F-FDG PET/CT诊断T分期特异度、准确度比较差异未见统计学意义(P>0.05)；18F-FDG PET/CT诊断T分期灵敏度(100.00%，21/21)高于CT诊断(66.67%，14/21)，P<0.05。CT和18F-FDG PET/CT诊断N分期特异度比较差异未见统计学意义(P>0.05)；18F-FDG PET/CT诊断N分期灵敏度(96.30%，26/27)、准确度(92.75%，64/69)高于CT诊断(48.15%，13/27；79.71%，55/69)，P<0.05。CT和18F-FDG PET/CT诊断M分期特异度、准确度比较差异未见统计学意义(P>0.05)；18F-FDG PET/CT诊断M分期灵敏度(100.00%，21/21)高于CT诊断(61.90%，13/21)，P<0.05。 结论 18 F-FDG PET/CT在老年食管癌分期诊断中应用价值良好，可提高诊断效能，为临床诊断提供科学依据。 Objective To analyze the application value of 18F-flurodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in staging diagnosis of esophageal cancer in elderly patients. Methods In the observational study, 69 elderly patients with esophageal cancer treated in Nanyang Central Hospital from April 2019 to August 2022 were selected, and they underwent conventional CT and 18F-FDG PET/CT for diagnosis. Taking the pathological results as the gold standard, the diagnostic results and diagnostic efficacy (sensitivity, specificity, accuracy) of 18F-FDG PET/CT and CT in the diagnosis of tumor-node-metastasis stage were compared. Results Among the 69 elderly patients with esophageal cancer, the pathological results showed 21 cases in T stage, 27 cases in N stage and 21 cases in M stage. There were no significant differences in the specificity and accuracy of CT and 18F-FDG PET/CT in diagnosis of T stage (P>0.05). The sensitivity of18F-FDG PET/CT in diagnosing T stage was 100.00% (21/21), which was higher than the 66.67% (14/21) of CT (P<0.05). There was no significant difference between CT and18F-FDG PET/CT in the diagnosis of N stage (P>0.05). The sensitivity and accuracy of18F-FDG PET/CT in the diagnosis of N stage were 96.30% (26/27) and 92.75% (64/69), respectively, which were higher than the 48.15% (13/27) and 79.71% (55/69) of CT (P<0.05). There were no significant differences in the specificity and accuracy of CT and18F-FDG PET/CT in the diagnosis of M stage (P>0.05). The sensitivity of18F-FDG PET/CT in diagnosing M stage was 100.00% (21/21), which was higher than the 61.90% (13/21) of CT (P<0.05). Conclusions 18F-FDG PET/CT has good application value in staging diagnosis of esophageal cancer in elderly patients, which can improve the diagnostic efficacy and provide scientific basis for clinical diagnosis.
Objective To analyze the application value of 18F-flurodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in staging diagnosis of esophageal cancer in elderly patients. Methods In the observational study, 69 elderly patients with esophageal cancer treated in Nanyang Central Hospital from April 2019 to August 2022 were selected, and they underwent conventional CT and 18F-FDG PET/CT for diagnosis. Taking the pathological results as the gold standard, the diagnostic results and diagnostic efficacy (sensitivity, specificity, accuracy) of 18F-FDG PET/CT and CT in the diagnosis of tumor-node-metastasis stage were compared. Results Among the 69 elderly patients with esophageal cancer, the pathological results showed 21 cases in T stage, 27 cases in N stage and 21 cases in M stage. There were no significant differences in the specificity and accuracy of CT and 18F-FDG PET/CT in diagnosis of T stage (P>0.05). The sensitivity of18F-FDG PET/CT in diagnosing T stage was 100.00% (21/21), which was higher than the 66.67% (14/21) of CT (P<0.05). There was no significant difference between CT and18F-FDG PET/CT in the diagnosis of N stage (P>0.05). The sensitivity and accuracy of18F-FDG PET/CT in the diagnosis of N stage were 96.30% (26/27) and 92.75% (64/69), respectively, which were higher than the 48.15% (13/27) and 79.71% (55/69) of CT (P<0.05). There were no significant differences in the specificity and accuracy of CT and18F-FDG PET/CT in the diagnosis of M stage (P>0.05). The sensitivity of18F-FDG PET/CT in diagnosing M stage was 100.00% (21/21), which was higher than the 61.90% (13/21) of CT (P<0.05). Conclusions 18F-FDG PET/CT has good application value in staging diagnosis of esophageal cancer in elderly patients, which can improve the diagnostic efficacy and provide scientific basis for clinical diagnosis.
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