Comparison of therapeutic effects of laparoscopic-assisted vaginal total hysterectomy versus traditional open hysterectomy on massive uterine fibroids
李琳 1张慧 1仝亚娟 1马艳丽
扫码查看
点击上方二维码区域，可以放大扫码查看
作者信息
1. 洛阳市第三人民医院 洛阳职业技术学院第一附属医院妇产科，洛阳 471002
折叠
摘要
目的 比较腹腔镜辅助阴式全子宫切除术与开腹子宫切除术治疗巨大子宫肌瘤的效果。 方法 回顾性抽取2020年1月至2022年12月洛阳市第三人民医院收治的巨大子宫肌瘤患者86例，依据术式分为研究组(49例)和对照组(37例)。研究组采用腹腔镜辅助阴式全子宫切除术治疗，对照组采用传统开腹子宫切除术治疗。比较两组围术期指标、并发症发生率、手术前后炎性指标和性激素水平。 结果 研究组手术时间、术后住院时间、术后下床时间短于对照组，术中出血量少于对照组，差异有统计学意义(P<0.05)。研究组术后并发症发生率(4.1%，2/49)低于对照组(21.6%，8/37)，P<0.05。术前，两组C反应蛋白、性激素水平比较差异未见统计学意义(P>0.05)；术后，两组C反应蛋白、促黄体生成素(LH)、促卵泡生成激素(FSH)水平高于术前，研究组C反应蛋白水平低于对照组，研究组LH、FSH水平高于对照组，差异有统计学意义(P<0.05)。 结论 腹腔镜辅助阴式全子宫切除术治疗巨大子宫肌瘤效果更佳，可缩短手术时间，减轻炎性反应程度。 Objective To compare the effects of laparoscopic-assisted vaginal total hysterectomy versus traditional open hysterectomy in the treatment of massive uterine fibroids. Methods Eighty-six patients with massive uterine fibroids admitted to Luoyang Third People’s Hospital from January 2020 to December 2022 were selected retrospectively, and the patients were divided into study group (49 cases) and control group (37 cases) according to the surgical procedure. The study group were treated by laparoscopic-assisted vaginal total hysterectomy, while the control group were treated by traditional open hysterectomy. The perioperative indicators, incidence of complications, preoperative and postoperative levels of inflammatory indicators, and sex hormones were compared between the two groups. Results The operative time, postoperative hospital stay and ambulation time in the study group were shorter than those in the control group, while the intraoperative blood loss of the study group was less than that of the control group (P<0.05). The incidence of postoperative complications in the study group (4.1%, 2/49) was lower than that in the control group (21.6%, 8/37),P<0.05. There was no significant in levels of C-reactive protein and sex hormones between the two groups before the operation (P>0.05). After the operation, the levels of C-reactive protein, luteinizing hormone (LH) and follicle stimulating hormone (FSH) of the two groups were significantly higher than those before the operation, however, the study group had lower level of C-reactive protein, higher level of LH and higher level of FSH compared with the control group (P<0.05). Conclusions Laparoscopic-assisted vaginal total hysterectomy is more effective in the treatment of massive uterine fibroids, which can shorten the operation time and reduce the degree of inflammatory response.
Abstract
Objective To compare the effects of laparoscopic-assisted vaginal total hysterectomy versus traditional open hysterectomy in the treatment of massive uterine fibroids. Methods Eighty-six patients with massive uterine fibroids admitted to Luoyang Third People’s Hospital from January 2020 to December 2022 were selected retrospectively, and the patients were divided into study group (49 cases) and control group (37 cases) according to the surgical procedure. The study group were treated by laparoscopic-assisted vaginal total hysterectomy, while the control group were treated by traditional open hysterectomy. The perioperative indicators, incidence of complications, preoperative and postoperative levels of inflammatory indicators, and sex hormones were compared between the two groups. Results The operative time, postoperative hospital stay and ambulation time in the study group were shorter than those in the control group, while the intraoperative blood loss of the study group was less than that of the control group (P<0.05). The incidence of postoperative complications in the study group (4.1%, 2/49) was lower than that in the control group (21.6%, 8/37),P<0.05. There was no significant in levels of C-reactive protein and sex hormones between the two groups before the operation (P>0.05). After the operation, the levels of C-reactive protein, luteinizing hormone (LH) and follicle stimulating hormone (FSH) of the two groups were significantly higher than those before the operation, however, the study group had lower level of C-reactive protein, higher level of LH and higher level of FSH compared with the control group (P<0.05). Conclusions Laparoscopic-assisted vaginal total hysterectomy is more effective in the treatment of massive uterine fibroids, which can shorten the operation time and reduce the degree of inflammatory response.
关键词
子宫肌瘤/巨大/腹腔镜辅助阴式全子宫切除术/C反应蛋白
Key words
Leiomyoma/Massive/Laparoscopic-assisted vaginal total hysterectomy/C-reactive protein
万方数据