Clinical observation of iRoot SP combined with single cone obturation in the treatment of endodontic disease
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目的 探讨iRoot SP配合单尖法根管充填治疗牙体牙髓病的临床效果。 方法 抽取2021年5月至2022年11月郑州大学第一附属医院收治的牙体牙髓病患者94例，依据随机数字表法分为对照组和观察组，每组47例。对照组采用iRoot SP配合冷侧压法根管充填治疗，观察组采用iRoot SP配合单尖法根管充填治疗。比较两组治疗效果、治疗后牙周指标[探诊深度(PD)、探诊出血指数(PBI)、菌斑指数(PLI)]、龈沟液炎症因子[肿瘤坏死因子－α(TNF－α)、C反应蛋白(CRP)、白细胞介素－1β(IL－1β)]水平、视觉模拟评分法(VAS)评分。 结果 观察组总有效率(97.87%，46/47)高于对照组(80.85%，38/47)，差异有统计学意义(P<0.05)。治疗后，观察组PD、PBI、PLI低于对照组，TNF－α、CRP、IL－1β水平低于对照组，VAS评分低于对照组，差异有统计学意义(P<0.05)。 结论 牙体牙髓病应用iRoot SP配合单尖法根管充填治疗效果显著，能改善牙周指标，减轻龈沟液炎症，缓解疼痛症状。 Objective To observe the clinical effect of iRoot SP combined with single cone obturation in the treatment of endodontic diseases. Methods A total of 94 patients with endodontic disease admitted to the First Affiliated Hospital of Zhengzhou University from May 2021 to November 2022 were selected, and they were divided into control group and observation group by random number table method, with 47 cases in each group. The control group was treated by iRoot SP combined with cold lateral pressure root canal filling, and the observation group was treated by iRoot SP combined with single cone obturation. The treatment effect, postoperative periodontal indexes, including probing depth (PD), probing bleeding index (PBI) and plaque index (PLI), levels of inflammatory factors in gingival crevicular fluid, including tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) and interleukin-1β (IL-1β), and visual analogue scale (VAS) score were compared between the two groups. Results The total effective rate of the observation group (97.87%, 46/47) was higher than that of the control group (80.85%, 38/47), and the difference was statistically significant (P<0.05). After treatment, the observation group had lower levels of PD, PBI, PLI, TNF-α, CRP and IL-1β compared with the control group (P<0.05), and the VAS score in the observation group was lower (P<0.05). Conclusions iRoot SP combined with single cone obturation has obvious effects in the treatment of endodontics, which can improve periodontal indexes, reduce levels of inflammation factors in gingival crevicular fluid, and relieve pain symptoms.
Objective To observe the clinical effect of iRoot SP combined with single cone obturation in the treatment of endodontic diseases. Methods A total of 94 patients with endodontic disease admitted to the First Affiliated Hospital of Zhengzhou University from May 2021 to November 2022 were selected, and they were divided into control group and observation group by random number table method, with 47 cases in each group. The control group was treated by iRoot SP combined with cold lateral pressure root canal filling, and the observation group was treated by iRoot SP combined with single cone obturation. The treatment effect, postoperative periodontal indexes, including probing depth (PD), probing bleeding index (PBI) and plaque index (PLI), levels of inflammatory factors in gingival crevicular fluid, including tumor necrosis factor-α (TNF-α), C-reactive protein (CRP) and interleukin-1β (IL-1β), and visual analogue scale (VAS) score were compared between the two groups. Results The total effective rate of the observation group (97.87%, 46/47) was higher than that of the control group (80.85%, 38/47), and the difference was statistically significant (P<0.05). After treatment, the observation group had lower levels of PD, PBI, PLI, TNF-α, CRP and IL-1β compared with the control group (P<0.05), and the VAS score in the observation group was lower (P<0.05). Conclusions iRoot SP combined with single cone obturation has obvious effects in the treatment of endodontics, which can improve periodontal indexes, reduce levels of inflammation factors in gingival crevicular fluid, and relieve pain symptoms.
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