Comparison of the clinical efficacy of allograft bone and xenogeneic bone in the periodontal regeneration of intrabony defects
Objective To compare the efficacy of allogeneic Bio-Gene and xenogenic Bio-Oss bone repair mate-rials using in guided tissue regeneration(GTR)combined with bone for the management of intrabony defects.Methods This retrospective study included 34 patients with periodontitis who still had intrabony defects after ini-tial periodontal therapy,and the patients were divided into the Bio-Gene group(n=16)and the Bio-Oss group(n=18)for the periodontal regeneration surgery with GTR combined with bone grafting.The periodontal probing depth(PD),clinical attachment level(CAL),gingival recession(GR),bleeding on probing(BOP),tooth mobility(TM),the distance from the cemento-enamel junction to the bottom of the bone defect(BD),intrabony defect depth(IBD),residual alveolar bone height(RBH)and bone defect angle(α)were compared between the two groups before periodontal regeneration(T0)and 12 months after periodontal regeneration(T1).Results Compared to T0,both groups showed significant improvements in PD,CAL,BOP,TM,BD,IBD,and RBH at T1(P＜0.05).When compared between the two groups at T1,difference between BD and RBH in the Bio-Gene group was significantly better than that in the Bio-Oss group(P＜0.05).Conclusion Both Bio-Gene and Bio-Oss can effectively improve the clinical effect of periodontal intrabony defects in a short time.It is worth no-ting that,in reducing BD,Bio-Gene demonstrates a superior performance compared to Bio-Oss.This provides new evidence for the treatment and clinical application of periodontal intrabony defects.
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