首页|三都水族自治县9154例妊娠期甲状腺功能检测结果分析

三都水族自治县9154例妊娠期甲状腺功能检测结果分析

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目的 了解三都水族自治县妊娠期甲状腺疾病患病现状,为制定干预策略提供参考依据。方法 回顾性分析2018年1月至2022年12月于三都水族自治县人民医院孕妇的病历资料,均具有甲状腺功能检测结果及年龄、孕周信息,分析妊娠期甲状腺疾病的发病率和患病特征。结果 2018年至2022年三都水族自治县妊娠期甲状腺功能异常率为11。23%(1 028/9 154),单因素分析显示低甲状腺素血症与孕龄相关,低甲状腺素血症、甲状腺功能减退症、亚临床甲状腺功能亢进症与孕期相关;Logistic回归分析提示高龄妊娠是低甲状腺素血症的危险因素(OR=2。184,P<0。01),孕中期发生亚临床甲状腺功能减退症(OR=2。470,P<0。01)和亚临床甲状腺功能亢进症(OR=2。680,P<0。01)的风险升高。结论 三都水族自治县妊娠期甲状腺疾病以甲状腺功能减退症最为常见,需建立地区特异性的妊娠期甲状腺功能参考区间确立诊断标准,同时加强孕期甲状腺功能监测并予以及时干预,以降低妊娠不良事件风险、促进妇幼健康。
Analysis of the results of thyroid function tests during pregnancy of 9 154 cases in Sandu shui autonomous county
Objective To investigate the current status of thyroid disease prevalence among pregnant females in Guizhou's Shui ethnic region,and to provide a referential basis for the development of intervention strategies.Methods The medical records of pregnant women admitted at the People's Hospital of Sandu Shui Nationality Autonomous County from January 2018 to December 2022 were retrospectively analysed(all of them had thyroid function test results and information on age and pregnancy week),so as to analyse the prevalence and prevalence characteristics of thyroid disorders during pregnancy.Results The rate of abnormal thyroid function in women during pregnancy in Guizhou Sui region from 2018 to 2022 was 11.23%(1 028/9 154),and univariate analysis showed that hypothyroxinemia was associated with pregnancy age,and hypothyroxinemia,hypothyroidism,and subclinical hyperthyroidism were associated with pregnancy duration;Logistic regression analysis suggested that advanced gestational age was a risk factor for hypothyroxinemia(OR=2.184,P<0.01),and there was an ele-vated risk of subclinical hypothyroidism(OR=2.470,P<0.01)and subclinical hyperthyroidism(OR=2.680,P<0.01)in the second trimester.Conclusion Hypothyroidism is the most common thyroid disorder in pregnant females in Guizhou's Shui region,and there is a need to establish region-specific reference intervals for thyroid function in pregnancy to establish diagnostic criteria,as well as to strengthen monitoring of thyroid func-tion during pregnancy and to provide timely interventions in order to reduce the risk of adverse events in pregnan-cy and improve the maternal and child health care.

thyroid hormonethyroid diseasethyroid functionpregnancy

吕俊远、黎卓璐、李颖、邹晓锋、陈均、陈胜元、余秋平、傅小云

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遵义医科大学附属医院晋通外科,贵州遵义 563099

遵义医科大学第一临床学院,贵州遵义 563099

三都水族自治县人民医院,贵州三都 558199

遵义医科大学附属医院妇产科,贵州遵义 563099

遵义医科大学附属医院重症医学科,贵州遵义 563099

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甲状腺激素 甲状腺功能 甲状腺疾病 妊娠

遵义医科大学大学生创新创业训练计划项目

ZYDC202302168

2024

遵义医科大学学报
遵义医科大学

遵义医科大学学报

CSTPCD
ISSN:2096-8159
年,卷(期):2024.47(2)
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