Application of electrospinning composite scaffold in bone tissue engineering
Serious bone abnormalities caused by congenital disorders,fractures,or tumors will result in diffi-cult to heal bone deformities once they exceed the body's self-healing potential.However,electrospun nanofiber scaffolds can mimic natural bone extracellular matrix,which can provide a favorable environment for cell adhe-sion,proliferation,and migration.Furthermore,it can be employed as a carrier to give the scaffold antibacteri-al,anti-inflammatory,and bone differentiation properties.The use of electrospinning scaffolds modified with bio-active compounds,medicines,and inorganic biomaterials in bone tissue regeneration engineering was reviewed in this study in order to give a theoretical foundation for the development of new bone regeneration materials.
bone tissue engineeringelectrospinningbone scaffold