Observation on the therapeutic effect of four different methods in the treat-ment of herpetic neuralgia at the first branch of the trigeminal nerve
Objective To compare and study the therapeutic effects of four commonly used methods in clinical treatment of herpes zoster neuralgia of the first branch of the trigeminal nerve.Methods A total of 52 patients di-agnosed with herpes zoster neuralgia in the first branch of the trigeminal nerve at the Pain Department of the Af-filiated Hospital Zunyi Medical University from July 2020 to July 2023 were analyzed.They were divided into four groups according to the treatment plan:10 cases in the SNB group(supraorbital nerve block),12 cases in the S-PRF group(supraorbital nerve pulsed radiofrequency treatment),13 cases in the TG-PRF group(trigeminal gan-glion pulse radiofrequency),and 17 cases in the PNS group(supraorbital nerve electrical stimulation treatment).The preoperative and postoperative NRS scores,number of pain outbreaks,dosage of pregabalin and tramadol,and PSQI scores among four groups were compared.Results Pain situation:Compared with preoperative baselines,the NRS score and number of pain outbreaks of the four groups of patients decreased at 1,4,and 12 weeks postopera-tively(P＜0.05).Four weeks after surgery,the NRS score of the SNB group was higher than the other three groups,while the NRS score of the PNS group was lower than the other three groups(P＜0.05);At 12 weeks post surgery,the NRS score and number of pain outbreaks in the PNS group were lower than those in the other three groups(P＜0.05).Sleep status:Compared with preoperative baseline,the PSQI scores of the four groups of patients decreased at 1,4,and 12 weeks postoperatively(P＜0.05).At 12 weeks post surgery,the PSQI score of the PNS group was lower than that of the other three groups(P＜0.05).Medication situation:Compared with preoperative,only the PNS group had a decrease in the dosage of pregabalin at 12 weeks post surgery.At 12 weeks after surgery,the dosage of pregabalin in the PNS group was significantly lower than that in the other three groups(P＜0.05).Compared with preoperative baselines,the dosage of tramadol in all four groups of patients decreased at 1,4,and 12 weeks postoperatively(P＜0.05).Inter group comparison showed that at 12 weeks post surgery,the dosage of tramadol in the PNS group was significantly lower than that in the other three groups.The incidence of PHN in the PNS group was lower than that in the other three groups(P＜0.05).Conclusion All four treatment methods can alleviate pain,improve sleep,reduce analgesic dosage,and lower the incidence of PHN.However,in terms of long-term effects,the effect of supraorbital nerve electrical stimulation is superior to the other three treatment methods.
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