Objective To describe a rare case of papillary thyroid carcinoma (PTC)combined with spinal giant cell tumor (GCTB),enhancing the medical understanding of both diseases,and explores the application of 3D printing technology in surgery,as well as the treatment methods and their effectiveness.Methods A 32-year-old female patient,after undergoing total thyroidectomy and lymph node dissection,sought medical attention for tho-racic and back pain and was ultimately diagnosed with spinal GCTB.During treatment,3D printing technology was utilized to assist in the surgical resection of GCTB and the reconstruction of the spine using a 3D-printed arti-ficial vertebra.Results The surgery successfully excisioned the GCTB and reconstructed the spine using 3D printing technology,resulting in good postoperative support and stability for the patient.Molecular pathology ex-amination revealed an H3F3A gene G34W missense mutation,which was consistent with the diagnosis of giant cell tumor of bone.Conclusion This case report enhances our understanding of the association between PTC and GCTB,emphasizing the importance of interdisciplinary collaboration and molecular biology in diagnosis and treat-ment.Additionally,this case showcases the application of 3D printing technology in spinal surgery,offering new perspectives and approaches for future surgical treatments.
关键词
甲状腺乳头状癌/骨巨细胞瘤/3D打印
Key words
papillary thyroid carcinoma/giant cell tumor of bone/3D printing
维普
万方数据