Comparative study and mid-term follow-up of platelet-rich plasma in the treatment of partial rotator cuff tears
Objective To explore the comparative study and mid-term efficacy of platelet-rich plasma (PRP)in-jection and block injection in the treatment of partial-thickness rotator cuff tears (PTRCT).Methods According to the inclusion criteria,50 patients with partial rotator cuff tears were selected and divided into experimental group and control group,with 25 cases in each group.The experimental group received PRP injection treatment,and the control group received block injection treatment.Shoulder joint flexion and extension range of motion (ROM),visual analogue scale (VAS),Constant-Murley shoulder score (CMS)and American Shoulder and El-bow Surgeons'form (ASES )were used to evaluate the shoulder function.For joint function,shoulder joint ROM,VAS,CMS and ASES scores were recorded before injection and at 1,3,6,12,24 and 36 months after injection.The rotator cuff healing status was evaluated by MRI of shoulder joint.Results No complications such as infection occurred in 50 patients during the (36±7.50)months follow up.The clinical efficacy of the two groups of patients after injection was better than that before injection over time.The ROM,VAS,CMS,and AS-ES of the block injection group were better than those of the PRP group 1 month after injection (P<0.01).The curative effects of the two groups were similar 3 months after injection,but there were statistical differences in abduction and internal rotation,VAS,CMS,and ASES in the abduction position (P<0.05).The block injec-tion group was better than the PRP group.There was no difference between the PRP group and the block injec-tion group 6 months after injection,and there was no difference between the two groups at 12,24,and 36 months after injection,but the VAS,CMS,and ASES of the PRP group were slightly better than those of the block injection group (P>0.05).At 12,24,and 36 months after injection,MRI of the shoulder joint showed that the partially torn rotator cuff healed better in the PRP group than in the block injection group.In the CMS score,the muscle strength of the PRP group was slightly better than that in then block injection group.The par-tially torn rotator cuff healed well compared with the block injection group,and better functionality showed some relevance.Conclusion PRP can promote the healing of PTRCT,and combined with rehabilitation therapy can in-crease joint mobility,relieve pain and improve function.Compared with shoulder joint block injection treatment,the mid-term follow-up results of PRP injection showed better rotator cuff healing rate and better functional score. Precise injection under ultrasound guidance can improve clinical efficacy.
万方数据
维普
