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增生性瘢痕早期防治的临床现状及展望

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增生性瘢痕是由伤口异常愈合引起的病理性瘢痕。其特点包括持续的局部炎症和过量的胶原蛋白沉积,这可能导致外观问题、挛缩畸形、功能丧失和心理问题等。目前,关于增生性瘢痕的临床治疗手段很多,但由于其发生机制尚未完全阐明,现有的临床治疗策略虽多样,包括物理治疗、光电治疗、药物治疗以及手术治疗等,但这些方法仍未能取得令人满意的效果。目前,早期多手段的综合干预已逐渐获得大多数临床医师的共识。本综述系统回顾了针对增生性瘢痕早期防治的临床研究现状,期望为增生性瘢痕的早期综合防治提供临床证据。
Clinical status and perspectives on the early management of proliferative scarring
Proliferative scarring is a pathological condition resulting from abnormal wound healing.Its charac-teristics include persistent local inflammation and excessive collagen deposition,which can lead to cosmetic is-sues,contractural deformities,functional impairment,and psychological distress.Although numerous clinical treatments for proliferative scarring are currently available,the underlying mechanisms of its formation remain in-adequately understood.Consequently,existing treatment strategies,while diverse (encompassing physical thera-py,phototherapy,pharmacological therapy,and surgical interventions),often fail to yield satisfactory outcomes. Recently,there has been a growing consensus among clinicians regarding the importance of early comprehensive intervention employing multiple approaches.This review systematically examines the current state of clinical studies focused on the early prevention and treatment of proliferative scarring,aiming to provide clinical evidence to support the implementation of comprehensive early prevention and treatment strategies.

hypertrophic scarpathological scarearly prevention and control

彭金梅、温印、聂开瑜

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遵义医科大学附属医院 烧伤整形外科,贵州 遵义 563000

增生性瘢痕 病理性瘢痕 早期防治

2024

遵义医科大学学报
遵义医科大学

遵义医科大学学报

CSTPCD
ISSN:2096-8159
年,卷(期):2024.47(12)