Isolation and Identification of Chemical Constituents of Phenolic Acids from the Leaves of Acanthopanax Senticosus Harms
Objective:To investigate the chemical constituents of the extracts from the leaves of Acanthopanax senticosus Harms.Methods:The chemical constituents were isolated by various isolation methods (silica gel ODS and HPLC column chromatography) and their structures were elucidated by the analysis of spectral data (NMR and MS).Results:Eight phenolic acids compounds were obtained as the following:caffeic acid (1),ferulic acid (2),protocatechuic acid methyl ester (3),protocatechuic acid (4),4-hydroxy-benzoic acid (5),syringic acid (6),chlorogenic acid (7),Coniferin (8).Conclusion:Compounds 2,3,5 are firstly isolated from this plant,and compounds 1,4,7,8 are firstly isolated from the leaves of this plant.