Changes of 5-hydroxymethylfurfuraldehyde Content in Radix Aconiti Tablets Processed at Different Time Points
Objective:To find the changing regularity of 5-Hydroxymethylfurfuraldehyde (5-HMF) content in Radix Aconiti tablets processed at different time points.Methods:HPLC was used to determine the changes of 5-HMF content in different processed products of Radix Aconiti.Results:The content of 5-HMF of the raw product was 4.45 μg/g.The content of 5-HMF was increased within the first six hours of heating.At the same processing time,the content of steamed products was significantly higher than that of boiled products.Conclusion:An HPLC method for determining the content of 5-HMF has been established.The proposed method is stable and reliable.The changes of the content of 5-HMF of Radix Aconiti tablets are processed by steaming and boiling for two kinds,which were associated with the heating time.It provides a reference for the quality control of Radix Aconiti.