基于络病理论探讨黄褐斑的病机
Pathogenesis Exploration of Melasma Based on Collateral Disease Theory
周爽 1魏云霞 1刘慧敏1
作者信息
- 1. 山东中医药大学,山东 济南 250355
- 折叠
摘要
以文献梳理络病学说的源流与发展历程,提出黄褐斑的基本病机为"斑毒-络伤-正虚",传变方式由气及血、由血入络.将络病理论与现代生物学机制相联系,认为黄褐斑皮损区炎症反应属气络亢变,真皮血管增生属血络亢变,其络脉虚亢本于络阴虚.因此,日久络伤、络脉亢变、虚实夹杂、本虚标实为黄褐斑核心病机.
Abstract
Based on literature review of the origin and development of collateral disease theory,it is proposed that the basic pathogenesis of melasma is"spot toxicity-collateral injury-healthy qi deficiency".The transmission is from qi to blood,and from blood to collateral.Combining the theory of collateral disease with the modern biological mechanism,we believe that the inflammatory reaction in the lesion area of melasma results from hyperactivity of qi collateral;while dermal angiogenesis is caused by hyperactivity of blood collateral;the essential reason of the collateral deficiency are resulted from collateral yin deficiency.Therefore,long-term disease damaging to the collateral,hyperactivity of the collateral,a mixture of deficiency and excess,and deficient root and excessive superficial are actually the core pathogenesis of melasma.
关键词
络病理论/黄褐斑/病机/络虚Key words
Collateral disease theory/Melasma/Pathogenesis/Deficiency of collaterals引用本文复制引用
基金项目
国家自然科学基金项目(81903948)
山东省自然科学基金项目(ZR2022MH181)
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据