Research Progress of Chemical Constituents,Pharmacological Action and Quality Marker Prediction of Largehead Atractylodes Rhizome
Largehead atractylodes rhizome is a commonly used as a major medicinal material,which can fortify the spleen,replenish qi,dry dampness and induce diuresis,be antagonistic to perspiration and prevent abortion.In this paper,we review the chemical constituents and pharmacological effects of the medicinal.On this basis,quality marker was predicted from the perspectives of plant affinity,component specificity,effectiveness,measurability and medicinal properties.We found that the chemical components of largehead atractylodes rhizome are diverse,including sesquiterpenoids,flavonoids,polysaccharides,polyacetylides,phenolic acids,glycosides and so on.These chemical components have anti-inflammatory,anti-tumor,gastrointestinal regulation,antibacterial,antioxidant,liver protection,cardiovascular and nervous system protection,immune regulation and other effects,and can be used for the treatment and prevention of gastrointestinal,nervous system and liver diseases.Lactone Ⅰ,Ⅱ,Ⅲ and other lactones and polysaccharide components can be used as alternative components of quality marker.