Clinical Study on Yitong Shu Pill in the Treatment of Ovarian Endometriosis Cysts
Objective:To explore the clinical efficacy and safety of Yitong Shu Pill(YSP)in the treatment of ovarian endometrial cysts(OEC).Methods:Sixty OEC patients who met the inclusion criteria were selected and randomly divided into a control group and an observation group based on a random number table,with 30 cases in each group.The control group received oral administration of denorgestrel,while the observation group received the same in addition to YSP.One menstrual cycle was considered as a course of treatment,and the treatment lasted for three consecutive courses.Changes in traditional Chinese medicine syndrome scores,maximum diameter of ectopic cysts,CA125,FSH,LH,and E2 levels before and after treatment in the two groups of patients were observed,and the clinical efficacy,traditional Chinese medicine syndrome efficacy,and adverse reactions in the two groups were compared.Results:After treatment,the total effective rate of traditional Chinese medicine syndromes in the observation group was 96.67%(29/30),while that of the control group was 76.67%(23/30),with a statistically significant difference(P<0.05).Total clinical effective rate was 93.33%(28/30)in the observation group and 73.33%(22/30)in the control group,and the difference was statistically significant(P<0.05).The traditional Chinese medicine syndrome scores of both groups decreased(P<0.05),and they decreased more in observation group than in the control group(P<0.05).The maximum diameter of ectopic cysts in both groups of patients decreased(P<0.05),and the diameter decreased more in the observation group than in the control group(P<0.05).The serum CA125 levels in both groups of patients decreased(P<0.05),and the observation group showed more significant compared to the control group(P<0.05).The serum levels of CA125,FSH,LH,and E2 in both groups of patients decreased,and the observation group was obvious compared with the control group(P<0.05).During the treatment process,there were no adverse reactions observed in both groups of patients.Conclusion:Yitong Shu Pill has a significant therapeutic effect on OEC,which can effectively improve clinical symptoms and signs of OEC patients,reduce traditional Chinese medicine syndrome scores,regulate serum levels of CA125,FSH,LH,and E2,reduce the size of ectopic cysts,and have a low incidence of adverse reactions.
Yitong Shu PillOvarian endometriotic cystCA125FSHLHE2
万方数据
维普
