Research Progress on the Material Basis and Mechanism of Anti-Inflammatory Activity of Red Paeony Root
Inflammation is a basic pathological process dominated by defensive reactions that occurs when biological tissues are stimulated by certain stimuli,such as trauma,infection and other injury factors.The development of inflammation may lead to variation and proliferation of local tissues,thus further accelerating the development of diseases.Red peony root is one of the most extensively used Chinese herbal medicinals,and has the actions of clearing heat,cooling blood,dispersing blood stasis,and relieving pain.By reviewing the recent literature on the material basis and mechanism of anti-inflammatory activity of red peony root,the authors found that terpenoids,volatile oils,phenolic acids,flavonoids,tannins and other chemical components in the medicinal exert anti-inflammatory effects through AMPK,MAPK,NF-κB,STAT6 and HO-1 signaling pathways,and therefore,it can be used to treat related inflammatory diseases such as colitis,arthritis,mastitis and keratitis.
Red Peony RootAnti-inflammationPhysical baseMechanism of actionReview
万方数据
维普
