Clinical Efficacy of Jianpi Qushi Jiedu Formula in Treating High Risk HPV Infection of the Cervix
Objective:To observe the clinical efficacy of Jianpi Qushi Jiedu Formula(JQJF)in the treatment of high-risk human papillomavirus(HR-HPV)infection in the cervix.Methods:Sixty-eight patients with cervical HR-HPV infection with splenic dampness-heat type meeting the inclusion criteria were selected and randomly divided into observation group and control group according to random number table,with 34 cases in each group.The control group was treated with recombinant human interferon α2b vaginal effervescent tablets,and the observation group was treated with the same in addition to oral JQJF,with 1 course of treatment for 3 months and 2 courses in total.The negative conversion rate of HR-HPV,clinical effective rate and TCM syndrome score before and after treatment were compared between the two groups.Results:There were 23 cases of HR-HPV negative transformation in the observation group and 14 cases in the control group.The rate of HR-HPV negative transformation in the observation group was significantly higher than that in the control group(P<0.05).After treatment,the TCM syndrome scores of both groups were lower than before treatment,and they were lower in the observation group than in the control group(P<0.01).The total effective rate of the observation group was 91.18%(31/34),and that of the control group was 70.59%(24/34),and the effective rate in the observation group was superior to that of the control group(P<0.05).Conclusion:Jianpi Qushi Jiedu Formula combined with recombinant human interferon α2b vaginal effervescent tablets can significantly improve the traditional Chinese medicine clinical symptoms of high-risk cervical HPV infection patients with spleen deficiency and dampness heat type,effectively eliminate persistent high-risk HPV infection and have good clinical efficacy.
Cervical HR-HPV infectionJianpi Qushi Jiedu FormulaTreating disease before its onsetDampnessToxinDeficiency
万方数据
维普
