Research Progress on Anti-Ovarian Cancer Mechanism of Active Components of Herba Epimedii:A Review
Ovarian cancer is one of the three major cancers of the female reproductive system,and its mortality rate ranks first among gynecological malignant tumors.Herba epimedii has the effect of tonifying kidney yang,strengthening sinew and bone,and dispelling wind and dampness,and is often used in the treatment of reproductive system diseases.This article reviews relevant literature at home and abroad and finds that the main active ingredients of Herba epimedii are icariin,icaritin,and icariside Ⅱ.This medicinal mainly exerts anti ovarian cancer effects from five aspects:promoting cell apoptosis,affecting cell invasion and metastasis,blocking cell cycle,inducing cell autophagy,and promoting cell pyroptosis.It can be seen that the herb can treat ovarian cancer through multiple targets and pathways.
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