Research Progress of Traditional Chinese Medicine in the Treatment of Ovarian Cancer
Ovarian cancer has the clinical characteristics of being difficult to detect,treat,and have a high recurrence rate,making it one of the most lethal gynecological malignancies.Its early symptoms are hidden,and when discovered,it has often progressed to the late stage.Postoperative platinum chemotherapy is currently the main treatment method,but long-term use can lead to drug resistance and numerous adverse reactions.In recent years,with the continuous progress and development of traditional Chinese medicine(TCM),TCM has become a hot topic in anti-ovarian cancer research.The author searched relevant research papers in domestic and foreign databases and found that Chinese herbal medicine has mechanisms of inhibiting ovarian cancer cell proliferation,promoting cell apoptosis,and reversing drug resistance.The effects are mainly obtained through acting on PI3K/Akt/mTOR,Wnt/β-Catenin,Notch,NF-κ B,and MAPK signaling pathways.
Traditional Chinese medicine monomerChinese herbal medicine extractChinese medicine formulaOvarian cancerSignaling pathway
国家科技期刊平台
NSTL
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