Research Progress of Leech Anticoagulant Components in the Treatment of Ischemic Stroke
Leech is a traditional Chinese animal herbal medicine for promoting blood circulation and removing blood stasis in China.Modern pharmacological studies have shown that Leech extract contains a large number of anticoagulant components and has a variety of pharmacological effects.Leech extract has a good clinical therapeutic effect on cardiovascular and cerebrovascular diseases.By reviewing the literature on the anticoagulant chemical components and their pharmacological effects in Leech,the author found that Leech contains peptides such as proteins,lipids,pteridins and other compounds.The anticoagulant compounds in Leech are the main active components in the medicinal,which have many pharmacological effects such as antithrombotic,anticoagulant,anti-atherosclerosis,anti-tumor and anti-inflammation.The mechanism of the treatment of ischemic stroke is related to improving coagulation,hemorheology and microcirculation,and repairing the damaged blood-brain barrier.
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