Effects of Modified Haizao Yuhu Decoction and Tounong Powder Combined with Fire Needle Therapy on Skin Physiological Function in Patients with Phlegm-Stasis Congealing Type Severe Acne
Objective:To explore the effects of modified Haizao Yuhu Decoction and Tounong Powder combined with fire needle therapy on skin physiological function in patients with phlegm-stasis congealing type severe acne.Methods:A total of 126 patients with phlegm-stasis congealing type severe acne meeting the inclusion criteria were randomly divided into a study group and a control group,with 63 patients in each group.The control group received conventional Western medicine treatment,while the study group received modified Haizao Yuhu Decoction and Tounong Powder combined with fire needle therapy.Both groups were treated for 8 weeks.The skin physiological functions(TEWL,epidermal moisture content,and sebum index),immune function(CD3+,CD4+,CD8+),and traditional Chinese medicine(TCM)symptom scores were measured before and after treatment,and clinical efficacy was compared between the two groups.Results:The total effective rate in the study group was 96.83%(61/63),significantly higher than 84.13%(53/63)in the control group(P<0.05).Post-treatment,TEWL levels in both groups decreased(P<0.05),while epidermal moisture content and sebum index increased(P<0.05).The study group showed a greater reduction in TEWL levels(P<0.01)and higher increases in epidermal moisture content and sebum index(P<0.05)compared to the control group.For immune function,CD3+and CD8+levels decreased(P<0.05)while CD4+levels increased(P<0.05)in the study group after treatment.When compared to the control group,the study group showed significantly lower levels of CD3+and CD8+(P<0.05,P<0.01)and higher CD4+levels(P<0.01).TCM symptom scores decreased significantly in both groups(P<0.05),with the study group showing a more significant reduction(P<0.01).Conclusion:The combined treatment of modified Haizao Yuhu Decoction and Tounong Powder combined with fire needle therapy significantly improves skin physiological function and immune function in patients with phlegm-stasis congealing type severe acne,with notable improvements in TCM clinical symptoms.
Haizao Yuhu DecoctionTounong PowderFire needlePhlegm-stasis congealing type severe acneSkin physiological functionImmune functionTCM symptom score
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维普
