Clinical outcomes and safety of moxibustion therapy combined with Tuina(推拿)therapy for treatment of lum-bar disc herniation:a meta-analysis
Objective:To systematically review the clinical outcomes and safety of moxibustion therapy combined with Tuina(推拿,TN)therapy for treatment of lumbar disc herniation(LDH).Methods:All the randomized controlled trial(RCT)articles about moxibustion therapy combined with TN therapy for treatment of LDH included from database establishing to December 31,2022 were retrieved from the PubMed,Cochrane Library,Embase,Chinese Biomedical Literature Service System,China National Knowledge Internet,Vip Database and Wanfang Database through computer.The patients in experimental group were treated with moxibustion therapy and TN therapy,while the ones in control group with TN therapy alone.The methodological quality of researches in the included articles was evaluated by using Co-chrane bias risk assessment tools,and then a Meta-analysis was conducted by using RevMan5.3 software.Results:Eight hundred and fifty-two articles were searched out.After screening,12 Chinese articles(1075 patients)were included in the final analysis,536 patients in exper-imental group and 539 ones in control group.The results of Meta-analysis revealed that the total clinical effective rate and Japanese Ortho-paedic Association(JOA)low back pain efficacy score were higher,while the pain visual analogue scale(VAS)score and Oswestry disability index(ODI)were lower in experimental group compared to control group(RR =1.18,95%CI(1.10,1.26),P =0.000;MD =3.77,95%CI(2.32,5.22),P =0.000;MD =-1.53,95%CI(-1.93,-1.13),P =0.000;MD =-2.28,95%CI(-4.40,-0.16),P =0.040);Furthermore,there was no statistical difference in incidence rate of adverse reactions between the 2 groups(OR =0.59,95%CI(0.08,4.58),P =0.620).Conclusion:Available evidences suggest that moxibustion therapy combined with TN therapy has good clinical out-comes and safety in treatment of LDH,and it surpasses the monotherapy of TN therapy in clinical outcomes.
intervertebral disc displacementlumbar vertebraemoxibustion(TCM)tui na therapymeta-analysis as topicefficacysafety