首页|骨质疏松性椎体压缩骨折椎体强化术后残余腰背痛的影响因素分析

骨质疏松性椎体压缩骨折椎体强化术后残余腰背痛的影响因素分析

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目的:分析骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fracture,OVCF)椎体强化术后残余腰背痛的影响因素。方法:回顾性分析采用椎体强化手术治疗的OVCF患者的病例资料,提取性别、年龄、体质量、是否合并糖尿病、是否合并高血压、是否有脊柱外伤史、是否合并Kümmell病、手术方式、骨水泥注入量、骨水泥分布情况、是否合并术后椎体感染、术前和术后1年椎体高度压缩比、术前和术后1年椎体后凸Cobb角及术后1年是否残余腰背痛等信息。根据术后1年患者是否残余腰背痛,将纳入研究的患者分为术后残余腰背痛组和术后无残余腰背痛组。先对2组患者的相关信息进行单因素分析,再采用多因素Logistic回归分析OVCF椎体强化术后残余腰背痛的影响因素。结果:共纳入602例OVCF患者,其中术后残余腰背痛组患者52例、术后无残余腰背痛组550例。2组患者是否有脊柱外伤史、是否合并Kümmell病、骨水泥注入量、骨水泥分布情况、术后1年椎体高度压缩比、术后1年椎体后凸Cobb角比较,组间差异均有统计学意义[x2=16。062,P=0。000;x2=6。453,P=0。011;(3。65±0。70)mL,(4。25±0。94)mL,t=-2。249,P=0。031;x2=12。366,P=0。000;(30。93±3。97)%,(23。21±4。02)%,t=6。917,P=0。000;12。41 °±3。69°,6。82°±2。63°,t=0。065,P=0。000]。Logistic 回归分析结果显示,合并 Kümmell 病、骨水泥分布不理想、术后1年椎体高度压缩比偏大、术后1年椎体后凸Cobb角偏大是OVCF椎体强化术后1年仍残余腰背痛的危险因素(β=1。682,P=0。031,OR=0。153;β=0。893,P=0。047,OR=2。202;β=0。635,P=0。014,OR=0。359;β=0。721,P=0。040,OR=0。762)。结论:合并Kümmell病、骨水泥分布不理想、术后椎体高度和椎体后凸畸形矫正不佳是OVCF椎体强化术后残余腰背痛的危险因素。
Factors influencing residual low back pain after vertebral augmentation for treatment of osteoporotic vertebral compression fracture
Objective:To analyze the factors influencing residual low back pain(LBP)after vertebral augmentation for treatment of os-teoporotic vertebral compression fracture(OVCF).Methods:The medical records of patients who underwent vertebral augmentation for treatment of OVCF were retrospectively analyzed.The information of the enrolled patients,including gender,age,body mass,whether com-bined with diabetes mellitus,hypertension,Kümmell's disease,and postoperative vertebral infection,spinal trauma history,operation me-thod,consumption and distribution of bone cement,preoperative and postoperative year-1 vertebral height compression ratio and kyphosis Cobb's angle,as well as whether presence of residual LBP at postoperative year-1,was extracted from the Electronic Medical Record System(EMRS).The included patients were divided into postoperative residual LBP group and postoperative non-residual LBP group based on whether the residual LBP was found at postoperative year-1.The single-factor analysis was conducted on the extracted information for screening the factors affecting residual LBP,followed by multi-factor logistic regression analysis on the screened factors for identifying the factors influencing residual LBP after vertebral augmentation for OVCF.Results:Six hundred and two patients were enrolled in the study,52 ones in postoperative residual LBP group and 550 ones in postoperative non-residual LBP group.The differences were statistically signifi-cant between the 2 groups in spinal trauma history,whether combined with Kümmell's disease,consumption of bone cement,distribution of bone cement,postoperative year-1 vertebral height compression ratio and kyphosis Cobb's angle(x2=16.062,P=0.000;x2=6.453,P=0.011;3.65±0.70 vs 4.25±0.94 mL,t=-2.249,P=0.031;x2=12.366,P=0.000;30.93±3.97 vs 23.21±4.02%,t=6.917,P=0.000;12.41±3.69 vs 6.82±2.63 degrees,t=0.065,P=0.000).The results of multi-factor logistic regression analysis showed that combined Kümmell's disease,suboptimal bone cement distribution,a greater vertebral height compression ratio at postoperative year-1,and a larger kyphosis Cobb's angle at postoperative year-1 were the risk factors for persistence of LBP at 1 year after vertebral augmentation for OVCF(β=1.682,P=0.031,OR=0.153;β=0.893,P=0.047,OR=2.202;β=0.635,P=0.014,OR=0.359;β=0.721,P=0.040,OR=0.762).Conclusion:Combined Kümmell's disease,suboptimal bone cement distribution,and poor correction of postoperative verte-bral height and kyphotic deformity are the risk factors for residual LBP after vertebral augmentation in patients with OVCF.

low back painback painosteoporotic fracturesspinal fracturesfractures,compressionvertebroplastykyphoplasty

张会、鄢卫平、刘卫义、郭广宇、李佳坤、段文帅、毛建伟

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甘肃中医药大学,甘肃 兰州 730000

甘肃省中医院,甘肃 兰州 730050

腰痛 背痛 骨质疏松性骨折 脊柱骨折 骨折,压缩性 椎体成形术 后凸成型术

2024

中医正骨
河南省正骨研究院

中医正骨

CSTPCD
影响因子:1.912
ISSN:1001-6015
年,卷(期):2024.36(8)