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基于乐观阴影集的荧光分子断层成像优化策略

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荧光分子断层成像(fluorescence molecular tomography,FMT)是一种很有潜力的光学分子影像技术,由于光在生物组织内传输时会产生大量随机的强散射,传播过程极其复杂,使得荧光分子断层成像重建具有高度的病态性.为了获得准确的重建结果,提出了一种基于乐观阴影集的FMT优化策略.首先,定义了一种基于阴影集的情绪决策—乐观决策和悲观决策.然后,提出了一种基于乐观决策的FMT优化策略,该策略将荧光产额信息转换为模糊信息样本,通过阴影集计算当前模糊信息样本的最佳阈值,对样本的划分采取乐观决策.最后,筛选出荧光目标的预测位置.实验结果表明,所提算法能够有效提高FMT重建的精度.
Optimization Strategy of FMT Based on Optimistic Shadowed Sets
Fluorescence molecular tomography (FMT) was a promising optical molecular imaging tech-nique.The transmission of light through biological tissues resulted in a substantial number of spontaneous and intense scatterings.The propagation process exhibited a high degree of complexity,contributing to a pronounced ill-posedness in the reconstruction of fluorescence molecular tomography.In order to obtain accurate and stable reconstruction results,an optimization strategy for FMT based on optimistic shadowed sets was proposed.Firstly,an emotional decision,including optimistic and pessimistic decisions,was defined based on shadow sets.Then,an optimization strategy for FMT based on the optimistic decision was introduced.The strategy could convert fluorescence yield information into fuzzy information samples as the membership degree of the fluorescence target,and calculated the optimal threshold of current fuzzy information samples by shadow set.Optimistic decision was adopted for the division of samples.Finally,the true position of fluorescent targets was selected.The experimental results indicated that the algorithm proposed effectively improved the accuracy of FMT reconstruction compared with the unoptimized FMT re-construction algorithm.

shadowed setsthree-way decisionfluorescence molecular tomographyoptimistic decision

张钦然、国栋凯、易黄建、谢琼

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西北大学信息与科学技术学院 陕西西安 710127

湖南中医药大学第一附属医院 湖南长沙 410208

阴影集 三支决策 荧光分子断层成像 乐观决策

2025

郑州大学学报(理学版)
郑州大学

郑州大学学报(理学版)

北大核心
影响因子:0.437
ISSN:1671-6841
年,卷(期):2025.57(1)